Giardino Luciano, Pontieri Francesco, Savoldi Enrico, Tallarigo Federico
Department of Periodontology, Dental, School, University of Brescia, Italy.
J Endod. 2006 Jul;32(7):692-4. doi: 10.1016/j.joen.2005.12.001. Epub 2006 Apr 4.
In nonimmunocompromised patients aspergillosis of the paranasal sinuses is a relatively rare disease. Root canal treated teeth with overextension of the root canal sealer or solid materials such as gutta-percha or silver cones into the sinus might be the main etiological factor for aspergillosis of the maxillary sinus in healthy patients. Root-filling materials based zinc oxide-eugenol is considered to be a growth factor for aspergillus. Aspergillus fumigatus needs heavy metals such as zinc oxide for proliferation and metabolism. Prognostic and histological studies showed that instrumentation and obturation should not extend beyond the apical foramen. When the sealer and/or gutta-percha is extruded within the sinus, this produce an inflammatory reaction and then Aspergillus growth. We report one case of healthy 60-yr-old male with overextension of root canal sealer in maxillary sinus. After surgical procedure, microscopic examination revealed aspergillosis. Overextension into the maxillary sinus with root canal cements has to be avoided.
在非免疫功能低下的患者中,鼻窦曲霉菌病是一种相对罕见的疾病。根管治疗后的牙齿,若根管封闭剂或诸如牙胶尖或银尖等固体材料超填至鼻窦内,可能是健康患者上颌窦曲霉菌病的主要病因。基于氧化锌-丁香酚的根管充填材料被认为是曲霉菌的生长因子。烟曲霉的增殖和代谢需要诸如氧化锌等重金属。预后和组织学研究表明,根管预备和充填不应超出根尖孔。当封闭剂和/或牙胶尖被挤出至鼻窦内时,会引发炎症反应,进而导致曲霉菌生长。我们报告一例60岁健康男性患者,其根管封闭剂超填至上颌窦。手术治疗后,显微镜检查显示为曲霉菌病。必须避免根管充填材料超填至上颌窦。