Chang Jerry S, Taouli Bachir, Salibi Nouha, Hecht Elizabeth M, Chin Deanna G, Lee Vivian S
Westwood Radiology Associates, Pascack Valley Hospital, Westwood, NY 07675, USA.
AJR Am J Roentgenol. 2006 Jul;187(1):W103-6. doi: 10.2214/AJR.05.0695.
The purpose of the study was to quantify the fat fraction in nine fat-water phantoms containing 0-80% fat using opposed-phase imaging with the qualitative guidance of 1H MR spectroscopy (MRS), which was used by observer 1 to visually assess the sizes of the water and fat peaks to apply two alternative mathematic formulas for the calculation of the fat fraction. In addition, the fat fraction was also quantified directly with 1H MRS as an independent method by two observers (observers 2 and 3).
The fat fraction calculated with opposed-phase imaging (FF(OPI)) and that calculated with 1H MRS (FF(MRS)) correlated well with the known fat fractions of the phantoms (FF(P)): r = 0.99 for FF(OPI); p < 0.0001 and r = 0.96-0.98 for FF(MRS); p < 0.001, for observers 2 and 3, respectively. Opposed-phase imaging should be combined with 1H MRS to ensure accurate quantification of the fat fraction.
本研究的目的是在1H磁共振波谱（MRS）定性指导下，使用反相位成像对九个含0 - 80%脂肪的脂肪-水模体中的脂肪分数进行定量。观察者1利用MRS在视觉上评估水峰和脂肪峰的大小，应用两种替代数学公式计算脂肪分数。此外，两名观察者（观察者2和观察者3）还使用1H MRS作为独立方法直接对脂肪分数进行定量。
用反相位成像计算的脂肪分数（FF(OPI)）和用1H MRS计算的脂肪分数（FF(MRS)）与模体已知脂肪分数（FF(P)）相关性良好：观察者1的FF(OPI)，r = 0.99；p < 0.0001；观察者2和观察者3的FF(MRS)，r分别为0.96 - 0.98；p < 0.001。反相位成像应与1H MRS相结合，以确保脂肪分数的准确量化。
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