Völzke Henry, Schwahn Christian, Dörr Marcus, Schwarz Sabine, Robinson Daniel, Dören Martina, Rettig Rainer, Felix Stephan B, John Ulrich, Kocher Thomas
Institute of Epidemiology and Social Medicine, Germany.
J Hypertens. 2006 Jul;24(7):1257-63. doi: 10.1097/01.hjh.0000234104.15992.df.
Tooth loss predicts total and circulatory mortality. The reasons for the increased mortality in subjects with a low number of teeth may be related to enhanced atherosclerosis, elevated arterial pressure and more frequent hypertension. The present study was designed to investigate whether there is an association between the number of teeth and arterial pressure or hypertension.
We used data of 4185 adult subjects (2150 women) collected for the population-based Study of Health in Pomerania. The number of teeth was counted by trained and certified dentists. Hypertension was defined as systolic blood pressure >or= 140 mmHg or diastolic blood pressure >or= 90 mmHg or use of antihypertensive medication. Multivariable analyses were adjusted for relevant confounders.
The adjusted mean (standard error) systolic blood pressure in men having 0-6 teeth was 149.6 mmHg (1.3 mmHg) compared to 142.6 mmHg (1.2 mmHg) in men having 27-28 teeth (P < 0.05). The adjusted odds for hypertension in men with 0-6 teeth compared to men with 27-28 teeth were 1.91 (95% confidence interval 1.21; 3.02, P < 0.05). In women no such relations were found.
There is an inverse association between the number of teeth and systolic blood pressure and hypertension in men but not in women. The present findings partly explain the relation between tooth loss and mortality.
牙齿缺失可预测全因死亡率和循环系统死亡率。牙齿数量少的受试者死亡率增加的原因可能与动脉粥样硬化加剧、动脉血压升高和高血压更为常见有关。本研究旨在调查牙齿数量与动脉血压或高血压之间是否存在关联。
我们使用了为基于人群的波美拉尼亚健康研究收集的4185名成年受试者(2150名女性)的数据。牙齿数量由经过培训并获得认证的牙医进行计数。高血压定义为收缩压≥140 mmHg或舒张压≥90 mmHg或使用抗高血压药物。多变量分析针对相关混杂因素进行了调整。
牙齿数量为0至6颗的男性,调整后的平均(标准误)收缩压为149.6 mmHg(1.3 mmHg),而牙齿数量为27至28颗的男性为142.6 mmHg(1.2 mmHg)(P<0.05)。牙齿数量为0至6颗的男性与牙齿数量为27至28颗的男性相比,高血压调整后的比值比为1.91(95%置信区间1.21;3.02,P<0.05)。在女性中未发现此类关系。
男性的牙齿数量与收缩压和高血压之间存在负相关,而女性则不然。本研究结果部分解释了牙齿缺失与死亡率之间的关系。