Nelson Katja, Ozyuvaci Hakan, Bilgic Bilge, Klein Martin, Hildebrand Detlef
Department of Oral and Maxillofacial Surgery, Clinical Navigation and Robotics, Charité-Campus Virchow Clinic, Berlin, Germany.
Int J Oral Maxillofac Implants. 2006 May-Jun;21(3):392-8.
In the present study solid monocortical hipbone onlay grafts of the maxilla were analyzed histologically after a healing period of 3 months. The clinical success of the implants placed in the grafted bone was evaluated.
Nineteen patients underwent augmentation with avascular iliac bone. A 2-stage procedure was performed with a 3-month healing period between graft and implant placement. At implant placement bone biopsy samples were taken at the proposed implant sites.
Of the 117 implants placed, 1 was not osseointegrated at the time of abutment connection. No implants were lost after loading during an observation period of up to 3 years. Clinical appearance of the augmented bone after 3 months showed a dense cortical layer with good blood perfusion. Histologic specimens were analyzed quantitatively and showed an average of 43.2% newly formed bone.
Histomorphometry showed that the amount of newly formed bone after 3 months was comparable to that found after a healing period of 4.5 months. The clinical success of the implants placed after the shortened healing period was comparable to that found in nonaugmented bone.
This study showed that after avascular iliac bone grafting, 3 months of revascularization was sufficient to ensure the secure placement of dental implants in second-stage surgery for this patient population.
在本研究中，对上颌骨单皮质实心贴附植骨在愈合3个月后的组织学情况进行分析，并评估植入到移植骨中的种植体的临床成功率。
19例患者接受了非血管化髂骨植骨术。采用两阶段手术，在植骨与种植体植入之间有3个月的愈合期。在种植体植入时，从拟植入种植体的部位获取骨活检样本。
在植入的117枚种植体中，1枚在基台连接时未实现骨结合。在长达3年的观察期内，加载后无种植体脱落。3个月后植骨的临床外观显示有一层致密的皮质层，血运良好。对组织学标本进行定量分析，结果显示平均有43.2%的新骨形成。
组织形态计量学显示，3个月后新形成骨的量与愈合4.5个月后观察到的量相当。缩短愈合期后植入种植体的临床成功率与非植骨部位相当。
本研究表明，对于该患者群体，非血管化髂骨植骨后3个月的血管化足以确保二期手术中种植体的安全植入。
