Sangi-Haghpeykar Haleh, Poindexter Alfred N
Baylor College of Medicine, Department of Obstetrics and Gynecology, Houston, TX 77030, United States.
Maturitas. 2007 Jan 20;56(1):30-7. doi: 10.1016/j.maturitas.2006.05.003. Epub 2006 Jun 21.
To examine physicians' views and practices concerning estrogen+progestogen therapy (EPT).
Questionnaires were mailed to a random sample of physicians in the United States (US) in 2003. A total of 1614 (53.8%) surveys were returned (633 obstetricians and gynecologists (Ob/Gyns), 571 family practitioners, and 410 internists).
Only a minority of the physicians (16%) would offer EPT to menopausal women in the absence of menopausal symptoms (26% Ob/Gyn, 11% family practitioners, 6% internists, p<0.0001). However, many physicians (62%) believed that EPT could be offered "short term" to menopausal women with menopausal symptoms assuming no contraindications (82% Ob/Gyn, 54% family practitioners, 42% internists; p<0.0001). Irrespective of specialty, the strongest contraindications to EPT use reported by these physicians were personal history of breast cancer (93%), thrombosis (92%), cerebrovascular disease (84%), ischemic heart disease (74%), uterine cancer (73%), as well as women's subjective "concern" about breast cancer (57%). Procedures reported as always required by physicians for continuing women on EPT were breast examination (97%), mammogram (96%), blood pressure measurement (94%), and pelvic examination (91%).
Internists and family practitioners address more contraindications to EPT use than Ob-Gyns. Although many physicians appear to be accepting of short-term use of EPT for menopausal indications in the absence of contraindications, the majority would not prescribe it for prophylactic purposes.
探讨医生对于雌激素加孕激素疗法(EPT)的观点和实践。
2003年向美国医生的随机样本邮寄了调查问卷。共收回1614份(53.8%)调查问卷(633名妇产科医生、571名家庭医生和410名内科医生)。
只有少数医生(16%)会在绝经后女性没有绝经症状时提供EPT(妇产科医生为26%,家庭医生为11%,内科医生为6%,p<0.0001)。然而,许多医生(62%)认为,在没有禁忌症的情况下,可以向有绝经症状的绝经后女性“短期”提供EPT(妇产科医生为82%,家庭医生为54%,内科医生为42%;p<0.0001)。无论专业如何,这些医生报告的EPT使用的最强禁忌症是乳腺癌个人史(93%)、血栓形成(92%)、脑血管疾病(84%)、缺血性心脏病(74%)、子宫癌(73%)以及女性对乳腺癌的主观“担忧”(57%)。医生报告的让女性继续使用EPT始终需要进行的检查是乳房检查(97%)、乳房X光检查(96%)、血压测量(94%)和盆腔检查(91%)。
内科医生和家庭医生比妇产科医生更关注EPT使用的禁忌症。尽管许多医生似乎接受在没有禁忌症的情况下短期使用EPT治疗绝经相关症状,但大多数医生不会出于预防目的而开这种药。