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肝移植术后鼻上颌部毛霉菌病感染的成功治疗:一例报告

Successful treatment of rhinomaxillary form of mucormycosis infection after liver transplantation: a case report.

作者信息

Vetrone G, Grazi G L, Ercolani G, Ravaioli M, Faenza S, Enrico B, Tumietto F, Pinna A D

机构信息

Liver and Multi-organ Transplantation, Sant 'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.

出版信息

Transplant Proc. 2006 Jun;38(5):1445-7. doi: 10.1016/j.transproceed.2006.02.102.

Abstract

Mucormycosis is a rare opportunistic infection, usually associated with immunocompromised states. Several conditions such as hematologic malignancy (leukemia, lymphoma, myeloma), solid organ transplantation, diabetes mellitus, corticosteroid therapy, or chemotherapy predispose patients to infection. The aim of this study was to present a single case of mucor infection after 900 consecutive liver transplantations. Rhinomaxillary mucormycosis must be suspected in a transplant recipient showing fever, maxillary swelling, and edema. This condition can be successfully treated with early diagnosis and a combination of aggressive surgery and antifungal therapy.

摘要

毛霉病是一种罕见的机会性感染,通常与免疫功能低下状态相关。血液系统恶性肿瘤(白血病、淋巴瘤、骨髓瘤)、实体器官移植、糖尿病、皮质类固醇治疗或化疗等多种情况会使患者易发生感染。本研究的目的是报告在连续900例肝移植术后出现的一例毛霉感染病例。对于出现发热、上颌肿胀和水肿的移植受者,必须怀疑有鼻上颌毛霉病。通过早期诊断以及积极手术和抗真菌治疗相结合,这种情况可以得到成功治疗。

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