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抑郁症患者持续性脑震荡后综合征的误诊

Misdiagnosis of the persistent postconcussion syndrome in patients with depression.

作者信息

Iverson Grant L

机构信息

Department of Psychiatry, University of British Columbia & Riverview Hospital, 2255 Wesbrook Mall, Vancouver, BC V6T 2A1, Canada.

出版信息

Arch Clin Neuropsychol. 2006 May;21(4):303-10. doi: 10.1016/j.acn.2005.12.008. Epub 2006 Jun 23.

DOI:10.1016/j.acn.2005.12.008
PMID:16797916
Abstract

The purpose of this study is to examine the prevalence of postconcussion-like symptoms in patients with depression. Participants were 64 physician-diagnosed inpatients or outpatients with depression who had independently-confirmed diagnoses on the Structured Clinical Interview for DSM-IV. All completed the British Columbia Postconcussion Symptom Inventory, a 16-item measure designed to assess the frequency and severity of symptoms based on ICD-10 criteria for postconcussion syndrome. Specific endorsement rates of postconcussion-like symptoms ranged from 31.2% to 85.6% for symptoms rated mild or greater, and from 10.9% to 57.8% for symptoms rated moderate-to-severe. Approximately 9 out of 10 patients with depression met liberal self-report criteria for a postconcussion syndrome and more than 5 out of 10 met conservative criteria for the diagnosis. Implications for forensic neuropsychology will be discussed.

摘要

本研究的目的是调查抑郁症患者中类似脑震荡后症状的患病率。研究参与者为64名经医生诊断的抑郁症住院或门诊患者,他们在《精神疾病诊断与统计手册》第四版(DSM-IV)的结构化临床访谈中得到了独立确认的诊断。所有人都完成了《不列颠哥伦比亚省脑震荡后症状量表》,这是一项包含16个条目的测量工具,旨在根据国际疾病分类第十版(ICD-10)中脑震荡后综合征的标准评估症状的频率和严重程度。对于评定为轻度或更严重的症状,类似脑震荡后症状的具体认可率在31.2%至85.6%之间;对于评定为中度至重度的症状,认可率在10.9%至57.8%之间。大约十分之九的抑郁症患者符合脑震荡后综合征的宽松自我报告标准,十分之五以上符合诊断的保守标准。将讨论对法医神经心理学的影响。

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