Verma A K, Raizada M K
Cell Differ. 1975 Jun;4(3):167-77. doi: 10.1016/0045-6039(75)90038-x.
During encystation of Hartmannella culbertsoni induced by taurine or epinephrine, 60-70% of the reserve glycogen is degraded. Glycogen phosphorylase is activated and glycogen synthetase is inhibited after 6-8 hr of exposure to the encystation medium. The carbon skeleton of glycogen but not that of protein is utilised in the synthesis of cyst wall cellulose. Exogenously added glucose (225 and 550 mM) blocks encystation, degradation of glycogen and synthesis of cellulose. Cyclic AMP synthesis is also very much reduced in cells exposed to glucose.
在由牛磺酸或肾上腺素诱导的库氏哈特曼氏变形虫包囊化过程中，60% - 70%的储备糖原会被降解。在暴露于包囊化培养基6 - 8小时后，糖原磷酸化酶被激活，糖原合成酶被抑制。糖原的碳骨架而非蛋白质的碳骨架被用于合成囊壁纤维素。外源添加的葡萄糖（225和550 mM）会阻断包囊化、糖原降解和纤维素合成。暴露于葡萄糖的细胞中，环磷酸腺苷的合成也会大幅减少。
