Pesudovs Konrad, Garamendi Estibaliz, Elliott David B
National Health and Medical Research Council (NH&MRC) Centre for Clinical Eye Research, Department of Ophthalmology, Flinders Medical Centre and Flinders University, Bedford Park, Australia.
Invest Ophthalmol Vis Sci. 2006 Jul;47(7):2789-96. doi: 10.1167/iovs.05-0933.
To develop and validate a questionnaire for the measurement of the impact of contact lenses on quality of life (QoL): The Contact Lens Impact on Quality of Life (CLIQ) Questionnaire.
The questionnaire was developed and validated using conventional methods and Rasch analysis to assure content validity, repeatability, construct validity, and low respondent burden. Item identification and selection (647 items) were performed with an extensive literature review, professional advice, and lay focus groups. Item reduction used focus groups and data obtained from 161 subjects completing a 90-item pilot questionnaire. Validity and reliability, from data of 128 additional subjects, were assessed using Rasch analysis, intraclass correlation coefficient, and Bland-Altman limits of agreement.
A 28-item CLIQ Questionnaire was developed and shown to have good validity and reliability by Rasch analysis statistics: real person separation, 2.02; model person separation, 2.17; reliability, 0.80; root mean square measurement error, 2.73; mean square+/-SD infit, 1.01+/-0.18; outfit, 1.01+/-0.19. The items (mean score, 49.8+/-4.9) were well targeted to the subjects (mean score, 51.2+/-6.2) with a mean difference of 1.35 (scale range, 0-100) units. Test-retest intraclass correlation coefficient (0.86) and coefficient of repeatability (+/-8.00 units) demonstrated good repeatability.
Rasch analysis and standard psychometric analyses demonstrated that the 28-item CLIQ Questionnaire is a valid and reliable measure of QoL in contact lens wearers. A scoring algorithm is provided for CLIQ Questionnaire users to convert raw scores into the Rasch analysis-derived linear person measures.
开发并验证一份用于测量隐形眼镜对生活质量（QoL）影响的问卷：隐形眼镜对生活质量影响（CLIQ）问卷。
采用传统方法和拉施分析来开发并验证该问卷，以确保内容效度、可重复性、结构效度及低应答负担。通过广泛的文献综述、专业建议和普通焦点小组进行项目识别与选择（647个项目）。项目缩减采用焦点小组以及从161名完成90项预测试问卷的受试者处获得的数据。利用拉施分析、组内相关系数和布兰德 - 奥特曼一致性界限，从另外128名受试者的数据评估效度和信度。
开发出一份28项的CLIQ问卷，通过拉施分析统计显示具有良好的效度和信度：真实个体分离度为2.02；模型个体分离度为2.17；信度为0.80；均方根测量误差为2.73；均方±标准差内拟合为1.01±0.18；外拟合为1.01±0.19。这些项目（平均得分49.8±4.9）与受试者（平均得分51.2±6.2）匹配良好，平均差异为1.35（量表范围为0 - 100）个单位。重测组内相关系数（0.86）和重复性系数（±8.00个单位）显示出良好的可重复性。
拉施分析和标准心理测量分析表明，28项的CLIQ问卷是测量隐形眼镜佩戴者生活质量的有效且可靠的工具。为CLIQ问卷使用者提供了一种计分算法，可将原始分数转换为拉施分析得出的线性个体测量值。
