Imelda Fitri, Bandar Ivo Novita Sah, Setiyohadi Bambang, Suwondo Pradana, Nasar I Made
Department of Internal Medicine, School of Medicine, University of Indonesia.
Acta Med Indones. 2006 Apr-Jun;38(2):89-91.
Osteoporosis can be primary or secondary. Secondary osteoporosis is the result of an underlying disease such as an endocrine abnormality, and an example of such is primary hyperparathyroidism. The most common cause of primary hyperparathyroidism is parathyroid gland adenoma. The diagnosis of primary hyperparathyroidism is based on the following biochemical examinations: parathyroid hormone, serum calcium, creatinine clearance, 24 hour urinary calcium, and another examination such as parathyroid gland scan. This is a rare case of an adult man who presented with a chief complaint of decreasing body height, back pain, difficulty in taking deep breaths and difficulty in his activities. The patient was diagnosed with primary hyperparathyroidism caused by parathyroid gland adenoma. His complaint was reduced after parathyroidectomy. His new complaint was that his tooth can be pulled out easily. We found high levels of parathyroid hormone and low levels of serum calcium caused by secondary hyperparathyroidism.
骨质疏松症可分为原发性或继发性。继发性骨质疏松症是由潜在疾病引起的,如内分泌异常,原发性甲状旁腺功能亢进就是其中一个例子。原发性甲状旁腺功能亢进最常见的病因是甲状旁腺腺瘤。原发性甲状旁腺功能亢进的诊断基于以下生化检查:甲状旁腺激素、血清钙、肌酐清除率、24小时尿钙,以及另一项检查,如甲状旁腺扫描。这是一例罕见的成年男性病例,其主要症状为身高下降、背痛、深呼吸困难和活动困难。该患者被诊断为甲状旁腺腺瘤引起的原发性甲状旁腺功能亢进。甲状旁腺切除术后,他的症状有所减轻。他新出现的症状是牙齿很容易被拔掉。我们发现该患者因继发性甲状旁腺功能亢进导致甲状旁腺激素水平升高,血清钙水平降低。