Venail Frederic, Nicollas Richard, Morin Denis, Mackle Tara, Garnier J M, Triglia Jean-Michel, Mondain Michel
Pediatric ENT Department, University Hospital Guide de Chauliac, Montpellier, France.
Laryngoscope. 2007 May;117(5):946-9. doi: 10.1097/MLG.0b013e3180337d95.
Solitary parathyroid adenoma is a rare cause of primary hyperparathyroidism in children. We report the cases of four children, aged 7 to 14 years old, who presented with a variety of symptoms (growth retardation, glomerulonephritis, pathological fracture, mood swings). Diagnosis was based on clinical examination, imaging, and biochemical analysis. Treatment consisted of surgical excision of the adenoma. As diagnosis was delayed in all four patients, we recommend systematically checking serum calcium levels in children with certain nonspecific symptoms. Adenoma resection usually restores normal serum calcium levels and, hence, avoids further complications.
孤立性甲状旁腺腺瘤是儿童原发性甲状旁腺功能亢进症的罕见病因。我们报告了4例年龄在7至14岁之间的儿童病例，这些儿童表现出各种症状（生长发育迟缓、肾小球肾炎、病理性骨折、情绪波动）。诊断基于临床检查、影像学检查和生化分析。治疗包括手术切除腺瘤。由于这4例患者的诊断均被延迟，我们建议对有某些非特异性症状的儿童系统地检查血清钙水平。腺瘤切除通常可使血清钙水平恢复正常，从而避免进一步的并发症。
