Pointis G, Mahoudeau J A, Courrier R
C R Acad Hebd Seances Acad Sci D. 1975 May 26;280(20):2361-4.
The production of testosterone (measured by radioimmuno-assay) by the 18-day-old mouse fetal testis may be stimulated specifically by ovine LH (1 ng, p less than 0.005) and HCG in organ culture. A stimulation by FSH is observed only with high doses (10 mug, p less than 0.0005). Prolactin and ACTH have no effect. Age-matched fetal pituitaries increase significantly the testosterone production in the culture medium (p less than 0.0005).
通过放射免疫测定法测量，在器官培养中，18日龄小鼠胎儿睾丸产生睾酮的过程可能会受到绵羊促黄体激素（1纳克，p<0.005）和人绒毛膜促性腺激素的特异性刺激。仅在高剂量（10微克，p<0.0005）时观察到促卵泡激素的刺激作用。催乳素和促肾上腺皮质激素没有作用。年龄匹配的胎儿垂体显著增加了培养基中睾酮的产生（p<0.0005）。
