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免疫功能正常宿主的尖孢镰刀菌肺炎

Fusarium oxysporum pneumonia in an immunocompetent host.

作者信息

Gorman Stephen R, Magiorakos Anna-Pelagia, Zimmerman Sarah K, Craven Donald E

机构信息

Department of Pulmonary and Critical Care Medicine, Lahey Clinic Medical Center, 41 Mall Road, Burlington, MA 01805, USA.

出版信息

South Med J. 2006 Jun;99(6):613-6. doi: 10.1097/01.smj.0000217160.63313.63.

Abstract

A case of symptomatic pulmonary infection caused by Fusarium oxysporum occurred in a woman after she had cleaned out bird droppings from a boat house. She was also a gardener who had mild, chronic obstructive lung disease, but who had no evidence of systemic immunosuppression. She was treated with oral voriconazole for four months and had marked clinical improvement and mycological cure. To the best of our knowledge, this is the first reported case of isolated pulmonary fusariosis in an apparently immunocompetent person. Oral voriconazole therapy was effective in this clinical setting.

摘要

一名女性在清理船屋的鸟粪后发生了由尖孢镰刀菌引起的有症状肺部感染。她还是一名园丁,患有轻度慢性阻塞性肺疾病,但无全身免疫抑制证据。她接受了四个月的口服伏立康唑治疗,临床症状显著改善,真菌学治愈。据我们所知,这是首例报道的在免疫功能看似正常的个体中发生的孤立性肺镰刀菌病病例。在这种临床情况下,口服伏立康唑治疗有效。

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