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在一名中性粒细胞减少患者中,长枝木霉引起的侵袭性肺部感染酷似侵袭性曲霉病,该患者接受伏立康唑联合卡泊芬净治疗成功。

Invasive pulmonary infection due to Trichoderma longibrachiatum mimicking invasive Aspergillosis in a neutropenic patient successfully treated with voriconazole combined with caspofungin.

作者信息

Alanio Alexandre, Brethon Benoît, Feuilhade de Chauvin Martine, de Kerviler Eric, Leblanc Thierry, Lacroix Claire, Baruchel André, Menotti Jean

机构信息

Department of Parasitology-Mycology, Saint-Louis Hospital, Assistance Publique-Hôpitaux de Paris, University of Paris, France.

出版信息

Clin Infect Dis. 2008 May 15;46(10):e116-8. doi: 10.1086/587750.

DOI:10.1086/587750
PMID:18419477
Abstract

Trichoderma longibrachiatum, a filamentous fungus, was recently described as an emerging pathogen in immunocompromised patients. Here, we report the first case, to our knowledge, of isolated invasive lung infection by T. longibrachiatum in a patient with hematologic malignancy. The infection mimicked invasive pulmonary aspergillosis and was successfully treated with a combination of voriconazole and caspofungin.

摘要

长枝木霉是一种丝状真菌,最近被描述为免疫功能低下患者中的一种新兴病原体。据我们所知,本文报告了首例长枝木霉引起的孤立性侵袭性肺部感染病例,该患者患有血液系统恶性肿瘤。该感染类似侵袭性肺曲霉病,通过伏立康唑和卡泊芬净联合治疗成功治愈。

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