严重血型不合胎儿进行血管内输血后的围产期结局

Perinatal outcome following intravascular transfusion in severely isoimmunized fetuses.

作者信息

Ney J A, Socol M L, Dooley S L, MacGregor S N, Silver R K, Millard D D

机构信息

Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, Illinois.

出版信息

Int J Gynaecol Obstet. 1991 May;35(1):41-6. doi: 10.1016/0020-7292(91)90061-9.

DOI:10.1016/0020-7292(91)90061-9

PMID:1680074

Abstract

Twenty-six severely isoimmunized pregnancies managed exclusively with ultrasonographically guided intravascular fetal transfusions are reported. The mean gestational age plus and minus one standard deviation (+/- SD) was 26.3 +/- 3.6 weeks and the mean hematocrit (+/- SD) prior to initial transfusion was 20.6 +/- 6.7%. Four of seven hydropic fetuses and 9 of 19 without hydrops were less than or equal to 26 weeks gestation at the first transfusion. Overall survival was 85% (22/26). Survival was similar whether or not fetal hydrops was present (6/7 vs. 16/19) and whether or not the first transfusion was administered at less than or equal to 26 weeks gestation (10/13 vs. 12/13).

摘要

本文报告了26例仅通过超声引导下血管内胎儿输血治疗的严重母儿血型不合妊娠病例。平均孕周（±1标准差）为26.3±3.6周，首次输血前平均血细胞比容（±标准差）为20.6±6.7%。7例水肿胎儿中有4例，19例非水肿胎儿中有9例在首次输血时孕周小于或等于26周。总体存活率为85%（22/26）。无论是否存在胎儿水肿（6/7对比16/19）以及首次输血时孕周是否小于或等于26周（10/13对比12/13），存活率相似。