McCalmont C S, Leshin B, White W L, Greiss F C, Jorizzo J L
Department of Dermatology, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, NC 27103.
Int J Gynaecol Obstet. 1991 Jun;35(2):175-8. doi: 10.1016/0020-7292(91)90823-n.
Pyoderma gangrenosum is an idiopathic dermatologic disease manifested by painful cutaneous ulceration. The ulcers are characterized by their undermined, violaceous borders and necrotic tissue at the ulcer base. The lesions may have an unusual response to physical manipulation known as pathergy, a phenomenon that is manifested by rapid progression following debridement. Pyoderma gangrenosum is frequently associated with systemic diseases such as inflammatory bowel disease, rheumatoid arthritis, chronic active hepatitis and hematologic malignancies. Conservative wound care and systemic corticosteroids are usually effective therapy. We report the second case in the gynecologic literature of a patient with vulvar pyoderma gangrenosum.
坏疽性脓皮病是一种特发性皮肤病，表现为疼痛性皮肤溃疡。溃疡的特征是边缘呈潜行性、紫红色，溃疡底部有坏死组织。病变对物理刺激可能有异常反应，即同形反应，这种现象表现为清创后迅速进展。坏疽性脓皮病常与系统性疾病相关，如炎症性肠病、类风湿关节炎、慢性活动性肝炎和血液系统恶性肿瘤。保守的伤口护理和全身性皮质类固醇通常是有效的治疗方法。我们报告了妇科文献中第二例患有外阴坏疽性脓皮病的患者。
