Jobe A H
Division of Pulmonary Biology Cincinnati Children's Hospital, University of Cincinnati School of Medicine, OH 45229, USA.
J Perinatol. 2006 Jul;26 Suppl 2:S5-7. doi: 10.1038/sj.jp.7211522.
The new biology has the potential to provide mechanistic insights into the causes and progression of complex cardiopulmonary diseases such as congenital heart disease and bronchopulmonary dysplasia. Such research requires collaborative investigation supported by sophisticated infrastructures and core facilities. Translating basic observations to clinical outcomes will require networks for collaborative translational research. The research initiatives require excellently trained and motivated clinician-scientists, but there are numerous barriers to the training and support of clinician-scientists in cardiology and neonatology.
新生物学有潜力为先天性心脏病和支气管肺发育不良等复杂心肺疾病的病因和进展提供机制性见解。此类研究需要由先进基础设施和核心设施支持的合作调查。将基础观察转化为临床结果需要开展合作转化研究的网络。这些研究计划需要训练有素且积极性高的临床科学家,但在心脏病学和新生儿学领域,临床科学家的培训和支持存在诸多障碍。