Rittweger J, Belavy D, Hunek P, Gast U, Boerst H, Feilcke B, Armbrecht G, Mulder E, Schubert H, Richardson C, de Haan A, Stegeman D F, Schiessl H, Felsenberg D
Centre for Muscle and Bone Research, Charité-Campus Benjamin Franklin, Berlin, Germany.
Int J Sports Med. 2006 Jul;27(7):553-9. doi: 10.1055/s-2005-872903.
Several studies have tried to find countermeasures against musculoskeletal de-conditioning during bed-rest, but none of them yielded decisive results. We hypothesised that resistive vibration exercise (RVE) might be a suitable training modality. We have therefore carried out a bed-rest study to evaluate its feasibility and efficacy during 56 days of bed-rest. Twenty healthy male volunteers aged 24 to 43 years were recruited and, after medical check-ups, randomised to a non-exercising control (Ctrl) group or a group that performed RVE 11 times per week. Strict bed-rest was controlled by video surveillance. The diet was controlled. RVE was performed in supine position, with a static force component of about twice the body weight and a smaller dynamic force component. RVE comprised four different units (squats, heel raises, toe raises, kicks), each of which lasted 60 - 100 seconds. Pre and post exercise levels of lactate were measured once weekly. Body weight was measured daily on a bed scale. Pain questionnaires were obtained in regular intervals during and after the bed-rest. Vibration frequency was set to 19 Hz at the beginning and progressed to 25.9 Hz (SD 1.9) at the end of the study, suggesting that the dynamic force component increased by 90 %. The maximum sustainable exercise time for squat exercise increased from 86 s (SD 21) on day 11 of the BR to 176 s (SD 73) on day 53 (p = 0.006). On the same days, post-exercise lactate levels increased from 6.9 mmol/l (SD2.3) to 9.2 mmol/l (SD 3.5, p = 0.01). On average, body weight was unchanged in both groups during bed-rest, but single individuals in both groups depicted significant weight changes ranging from - 10 % to + 10 % (p < 0.001). Lower limb pain was more frequent during bed-rest in the RVE subjects than in Ctrl (p = 0.035). During early recovery, subjects of both groups suffered from muscle pain to a comparable extent, but foot pain was more common in Ctrl than in RVE (p = 0.013 for plantar pain, p = 0.074 for dorsal foot pain). Our results indicate that RVE is feasible twice daily during bed-rest in young healthy males, provided that one afternoon and one entire day per week are free. Exercise progression, mainly by progression of vibration frequency, yielded increases in maximum sustainable exercise time and blood lactate. In conclusion, RVE as performed in this study, appears to be safe.
多项研究试图找到应对卧床休息期间肌肉骨骼机能衰退的对策，但均未取得决定性成果。我们推测，阻力振动训练（RVE）可能是一种合适的训练方式。因此，我们开展了一项卧床休息研究，以评估其在56天卧床休息期间的可行性和效果。招募了20名年龄在24至43岁之间的健康男性志愿者，在进行医学检查后，随机分为非运动对照组（Ctrl）或每周进行11次RVE的组。通过视频监控严格控制卧床休息。饮食也受到控制。RVE在仰卧位进行，静态力分量约为体重的两倍，动态力分量较小。RVE包括四个不同的单元（深蹲、提踵、踮脚尖、踢腿），每个单元持续60 - 100秒。每周测量一次运动前后的乳酸水平。每天在床秤上测量体重。在卧床休息期间及之后定期获取疼痛问卷。振动频率在开始时设定为19 Hz，在研究结束时升至25.9 Hz（标准差1.9），这表明动态力分量增加了90%。深蹲运动的最大可持续运动时间从卧床休息第11天的86秒（标准差21）增加到第53天的176秒（标准差73）（p = 0.006）。在同一天，运动后乳酸水平从6.9 mmol/l（标准差2.3）增加到9.2 mmol/l（标准差3.5，p = 0.01）。平均而言，两组在卧床休息期间体重均未改变，但两组中的个体体重均有显著变化，范围从 - 10%到 + 10%（p < 0.001）。RVE组的受试者在卧床休息期间下肢疼痛比对照组更频繁（p = 0.035）。在早期恢复期间，两组受试者肌肉疼痛程度相当，但对照组足部疼痛比RVE组更常见（足底疼痛p = 0.013，足背疼痛p = 0.074）。我们的结果表明，对于年轻健康男性，只要每周有一个下午和一整天空闲时间，RVE在卧床休息期间每天进行两次是可行的。运动进展主要通过振动频率的提高实现，这使得最大可持续运动时间和血乳酸增加。总之，本研究中所进行的RVE似乎是安全的。
