Ferreri Florinda, Curcio Giuseppe, Pasqualetti Patrizio, De Gennaro Luigi, Fini Rita, Rossini Paolo Maria
Department of Neurology, University Campus Biomedico, Isola Tiberina.
Ann Neurol. 2006 Aug;60(2):188-96. doi: 10.1002/ana.20906.
To test-via Transcranial Magnetic Stimulation (TMS)-the excitability of each brain hemisphere after 'real' or 'sham' exposure to the electromagnetic field (EMF) generated by a mobile phone operating in the Global System for Mobile Communication (GSM).
Fifteen male volunteers attended two experimental sessions, one week apart, in a cross-over, double-blind paradigm. In one session the signal was turned ON (EMF-on, real exposure), in the other it was turned OFF (EMF-off, sham exposure), for 45 minutes. Motor Evoked Potentials (MEPs) were recorded using a paired-pulse paradigm (testing intracortical excitability with 1 to 17 ms interstimulus intervals), both before and at different times after exposure to the EMF. Short Intracortical Inhibition (SICI) and Facilitation (ICF) curves were evaluated both on the exposed and non-exposed hemispheres. Tympanic temperature was collected during each session.
The intracortical excitability curve becomes significantly modified during real exposure, with SICI being reduced and ICF enhanced in the acutely exposed brain hemisphere as compared to the contralateral, non-exposed hemisphere or to sham exposure. Tympanic temperature showed no significant main effect or interactions.
These results demonstrate that GSM-EMFs modify brain excitability. Possible implications and applications are discussed.
通过经颅磁刺激（TMS）测试在“真实”或“假”暴露于全球移动通信系统（GSM）运行的手机所产生的电磁场（EMF）后每个脑半球的兴奋性。
15名男性志愿者以交叉、双盲模式参加了两次实验，间隔一周。在一次实验中，信号开启（EMF开启，真实暴露），在另一次实验中，信号关闭（EMF关闭，假暴露），持续45分钟。在暴露于EMF之前和之后的不同时间，使用配对脉冲模式（以1至17毫秒的刺激间隔测试皮质内兴奋性）记录运动诱发电位（MEP）。在暴露和未暴露的半球上评估短皮质内抑制（SICI）和易化（ICF）曲线。在每次实验期间收集鼓膜温度。
在真实暴露期间，皮质内兴奋性曲线发生显著改变，与对侧未暴露半球或假暴露相比，急性暴露的脑半球的SICI降低，ICF增强。鼓膜温度未显示出显著的主效应或交互作用。
这些结果表明GSM-EMF会改变大脑兴奋性。讨论了可能的影响和应用。
Zotero 插件