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宫颈上皮内瘤变治疗中环形电切术前的心理疾病

Psychologic morbidities prior to loop electrosurgical excision procedure in the treatment of cervical intraepithelial neoplasia.

作者信息

Le T, Hopkins L, Menard C, Hicks-Boucher W, Lefebvre J, Fung Kee Fung M

机构信息

Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Newborn Care, University of Ottawa, Ottawa General Hospital, 501 Smyth Road, Ottawa, Ontario, Canada.

出版信息

Int J Gynecol Cancer. 2006 May-Jun;16(3):1089-93. doi: 10.1111/j.1525-1438.2006.00599.x.

Abstract

The objective of this study was to assess and compare anxiety and distress in patients undergoing colposcopic examinations and loop electrosurgical excision procedure (LEEP). Patients seen for evaluation of cervical intraepithelial neoplasia (CIN) and LEEP were recruited. All patients received further teaching with respect to their abnormality right after the colposcopic evaluation by nursing staff. The Hospital anxiety and Depression Scale (HADS) and the Psychosocial Effects of Abnormal Pap Smears (PEAPS) questionnaires were used to measure and compare distress between the two groups. Linear regression models were built to identify significant predictive variables for psychologic morbidities. Twenty-one colposcopy and 20 LEEP patients participated in this study. No significant demographic differences were noted. Eighty-one percent of patients having colposcopy and 65% of those undergoing LEEP can be classified as having significant anxiety and depression based on the HADS questionnaire. Patients undergoing LEEP scored significantly better than colposcopy patients on the mean total PEAPS score and on the self-belief/cancer concern and effects on sexual relationship dimension scores. Significant psychologic morbidities exist in patients diagnosed with CIN. Face-to-face individualized education and support after colposcopy can decrease patients' distress at subsequent treatment visits.

摘要

本研究的目的是评估和比较接受阴道镜检查及环形电切术(LEEP)的患者的焦虑和痛苦程度。招募因宫颈上皮内瘤变(CIN)接受评估及LEEP的患者。所有患者在阴道镜评估后,由护理人员就其异常情况接受进一步指导。使用医院焦虑抑郁量表(HADS)和巴氏涂片异常的社会心理影响(PEAPS)问卷来测量和比较两组患者的痛苦程度。构建线性回归模型以确定心理疾病的显著预测变量。21名接受阴道镜检查的患者和20名接受LEEP的患者参与了本研究。未发现显著的人口统计学差异。根据HADS问卷,81%接受阴道镜检查的患者和65%接受LEEP的患者可被归类为有显著焦虑和抑郁。接受LEEP的患者在PEAPS总均分、自我信念/癌症担忧以及对性关系维度得分方面显著优于接受阴道镜检查的患者。被诊断为CIN的患者存在显著的心理疾病。阴道镜检查后进行面对面的个性化教育和支持可减少患者在后续治疗就诊时的痛苦。

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