Karzon Roanne K, Lieu Judith E Cho
St. Louis Children's Hospital, One Children's Place, Room 3S23, St. Louis, MO 63110, USA.
Am J Audiol. 2006 Jun;15(1):14-24. doi: 10.1044/1059-0889(2006/003).
The purpose of the study was to evaluate the effectiveness of a 2-hr initial audiologic assessment appointment for infants referred from area universal newborn hearing screening (UNHS) programs to a clinical audiology department in an urban hospital.
A prospective auditory brainstem response (ABR)-based protocol, including clicks, frequency-specific tone bursts, and bone-conducted stimuli, was administered by 10 audiologists to 375 infants. Depending on the ABR findings, additional test options included distortion product otoacoustic emissions (DPOAEs), high-frequency tympanometry, and/or otologic examination.
In 88% of the 2-hr test sessions, at least 4 ABR threshold estimates were obtained (i.e., bilateral clicks and either a 500- or 1000-Hz tone burst and a 4000-Hz frequency tone burst for the better ear). The incidence of hearing loss was significantly different across nursery levels: 18% for Level I (well baby), 29% for Level II (special care), and 52% for Level III (neonatal intensive care unit). Hearing loss type was defined at the initial assessment for 35 of the 51 infants with bilateral hearing loss based on bone-conduction ABR, latency measures, DPOAEs, high-frequency tympanometry, and/or otologic examination.
Our findings indicate that a 2-hr test appointment is appropriate for all nursery levels to diagnose severity and type of hearing loss in the majority of infants referred from UNHS. Examination by an otolaryngologist within 24-48 hr further defines the hearing loss and facilitates treatment plans.
本研究旨在评估在一家城市医院,对于从地区新生儿听力普遍筛查(UNHS)项目转诊至临床听力学科室的婴儿,进行为期2小时的初始听力学评估预约的有效性。
10名听力学家采用基于听觉脑干反应(ABR)的前瞻性方案,对375名婴儿进行检查,该方案包括短声、特定频率的短纯音以及骨导刺激。根据ABR检查结果,其他测试选项包括畸变产物耳声发射(DPOAE)、高频鼓室图和/或耳科检查。
在88%的2小时测试时段中,至少获得了4次ABR阈值估计值(即双耳短声以及较好耳的500赫兹或1000赫兹短纯音和4000赫兹频率短纯音)。不同护理级别婴儿的听力损失发生率存在显著差异:一级(健康婴儿)为18%,二级(特殊护理)为29%,三级(新生儿重症监护病房)为52%。根据骨导ABR、潜伏期测量、DPOAE、高频鼓室图和/或耳科检查,在51名双侧听力损失婴儿中的35名婴儿的初始评估中确定了听力损失类型。
我们的研究结果表明,对于所有护理级别而言,2小时的测试预约足以诊断大多数从UNHS转诊的婴儿的听力损失严重程度和类型。在24至48小时内由耳鼻喉科医生进行检查可进一步明确听力损失情况并有助于制定治疗计划。