抗中性粒细胞胞浆抗体（ANCA）阳性血管炎患者皮肤溃疡处的巨细胞病毒感染。

Cytomegalovirus infection of a cutaneous ulcer in a patient with ANCA-positive vasculitis.

作者信息

Nolan Richard C, Sadler Genevieve M, Forrest Cynthia H, Stacey Michael C, Mallon Dominic F

机构信息

Department of Immunology, Level 4 B Block, Fremantle Hospital, Alma Street, Fremantle, WA 6160, Australia.

出版信息

Clin Rheumatol. 2007 May;26(5):829-30. doi: 10.1007/s10067-006-0361-8. Epub 2006 Jun 28.

DOI:10.1007/s10067-006-0361-8

PMID:16804736

Abstract

This case describes a patient in whom cytomegalovirus (CMV) infected a preexisting ulcer. The patient was immune-suppressed because of treatment for Wegener's granulomatosis. Specific antiviral therapy was delayed because of uncertainty as to the role of CMV, but the infection cleared and the ulcer improved promptly on institution of valganciclovir.

摘要

该病例描述了一名巨细胞病毒（CMV）感染已存在溃疡的患者。患者因韦格纳肉芽肿的治疗而免疫抑制。由于对CMV作用的不确定性，特异性抗病毒治疗被推迟，但在使用缬更昔洛韦后感染清除且溃疡迅速改善。