Borman Andrew M, Campbell Colin K, Linton Christopher J, Bridge Paul D, Johnson Elizabeth M
Mycology Reference Laboratory, Health Protection Agency South-West Regional Laboratory Myrtle Road, Bristol, UK.
Med Mycol. 2006 Feb;44(1):33-9. doi: 10.1080/13693780500179678.
PCR amplification and sequencing of two separate regions of the nuclear ribosomal repeat region revealed that Polycytella hominis, a hyphomycete isolated from a human case of mycetoma, was genetically indistinguishable from Scedosporium apiospermum (the anamorph of Pseudallescheria boydii). These organisms also exhibited remarkably similar susceptibility profiles to common antifungal agents. P. hominis is thus likely to be a mutant of S. apiospermum showing abnormalities of sporulation, for which a possible mechanism is discussed. Polycytella hominis should thus be regarded as a synonym of Scedosporium apiospermum.
对核糖体重复区域的两个独立区域进行聚合酶链反应(PCR)扩增和测序后发现,从一例人类足菌肿病例中分离出的丝状真菌人多胞菌,在基因上与尖端赛多孢子菌(波氏假阿利什菌的无性型)无法区分。这些微生物对常见抗真菌药物的敏感性谱也表现出显著相似性。因此,人多胞菌可能是尖端赛多孢子菌的一个表现出孢子形成异常的突变体,并对此可能的机制进行了讨论。因此,人多胞菌应被视为尖端赛多孢子菌的同义词。