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完整尿路切除:马里兰大学的经验

Complete urinary tract extirpation: the University of Maryland experience.

作者信息

Holton Mara R, Van Zijl P Sean, Oberle W Todd, Jacobs Stephen C, Sklar Geoffrey N

机构信息

Division of Urology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.

出版信息

Urology. 2006 Jul;68(1):65-9. doi: 10.1016/j.urology.2006.01.045. Epub 2006 Jun 27.

Abstract

OBJECTIVES

Complete urinary tract extirpation (CUTE) involves simultaneous bilateral nephroureterectomy, cystectomy or cystoprostatectomy, and the creation of a urinary diversion, if needed. Case reports of this operation have been published, but to our knowledge, this is the largest case series yet reported. We sought to evaluate the characteristics and outcomes of patients who underwent CUTE.

METHODS

From 1994 to 2005, 9 patients underwent CUTE at our institution. We performed a retrospective chart review of these patients. The data reviewed included demographics, operative time, length of stay, complications, recurrences, and overall survival.

RESULTS

Nine patients who underwent CUTE were identified. The mean patient age at the operation was 61 years. Five patients were men. The mean operative time was 356 minutes. Two patients required a blood transfusion. The length of stay averaged 10.8 days (range 6 to 47). Four patients had functioning renal allografts before and after surgery. Three patients needing dialysis received renal allografts postoperatively. The overall survival rate at a mean follow-up of 31 months was 86%.

CONCLUSIONS

Although this report presented a small number of patients, it has illustrated that CUTE can be performed safely and allow definitive surgical treatment of patients with complex genitourinary pathologic findings.

摘要

目的

完全性尿路切除术(CUTE)包括同时进行双侧肾输尿管切除术、膀胱切除术或膀胱前列腺切除术,如有需要则进行尿流改道。关于该手术的病例报告已有发表,但据我们所知,这是迄今报道的最大病例系列。我们旨在评估接受CUTE手术患者的特征和预后。

方法

1994年至2005年,我们机构有9例患者接受了CUTE手术。我们对这些患者进行了回顾性病历审查。审查的数据包括人口统计学资料、手术时间、住院时间、并发症、复发情况和总生存率。

结果

确定了9例接受CUTE手术的患者。手术时患者的平均年龄为61岁。5例为男性。平均手术时间为356分钟。2例患者需要输血。住院时间平均为10.8天(范围为6至47天)。4例患者手术前后均有功能正常的肾移植。3例需要透析的患者术后接受了肾移植。平均随访31个月时的总生存率为86%。

结论

尽管本报告中的患者数量较少,但已表明CUTE手术可以安全进行,并能对有复杂泌尿生殖系统病理表现的患者进行确定性手术治疗。

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