Abouzahir A, Baite A, Azennag M, Bouchama R, Nzouba L
Service de médecine interne, 5e hôpital militaire, BP 1052, 81000 Guelmim, Maroc.
Rev Med Interne. 2006 Aug;27(8):640-2. doi: 10.1016/j.revmed.2006.03.036. Epub 2006 Jun 5.
The association of pancreatitis and hyperparathyroidism is rare.
A 41-year-old man had consulted for a strong abdominal pain reliant to a chronic calcifying pancreatitis. A major hypercalcaemia led to a primary hyperparathyroidism diagnosis. The evolution was favourable after parathyroid adenoma surgery.
The hypercalcaemia activate the transformation of trypsinogen into trypsin which is toxic for the pancreas. The role of parathyroid hormone remains unclear.
胰腺炎与甲状旁腺功能亢进的关联较为罕见。
一名41岁男性因慢性钙化性胰腺炎引发的剧烈腹痛前来就诊。严重高钙血症导致原发性甲状旁腺功能亢进的诊断。甲状旁腺腺瘤手术后病情进展良好。
高钙血症促使胰蛋白酶原转化为对胰腺有毒性的胰蛋白酶。甲状旁腺激素的作用尚不清楚。
