马的胃肠动力——肠梗阻与药物调节
Equine gastrointestinal motility--ileus and pharmacological modification.
作者信息
Koenig Judith, Cote Nathalie
机构信息
Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1.
出版信息
Can Vet J. 2006 Jun;47(6):551-9.
Abstract
Colic is a common problem encountered in equine practice. Alteration of gastrointestinal motility is often the underlying cause for abdominal pain. Gastrointestinal motility can be measured as myoelectric activity, mechanical activity, and transit of intraluminal contents. Regulation of motility is based on a complex interaction between central innervation, autonomic innervation, and the enteric nervous system. Various humoral and neurochemical substances are required to interact flawlessly to allow propulsive motility. Ileus is defined as the absence of propulsive aboral movement of gastrointestinal contents, irrespective of its pathophysiology. Potential etiologies for ileus are described in this review. The prokinetic drugs available for clinical use are discussed. Choosing the appropriate prokinetic drug requires knowledge about the complex nature of gastrointestinal motility and its abnormalities.
摘要
疝痛是马匹临床实践中常见的问题。胃肠动力改变常常是腹痛的根本原因。胃肠动力可通过肌电活动、机械活动及肠腔内内容物的转运来衡量。动力的调节基于中枢神经支配、自主神经支配及肠神经系统之间的复杂相互作用。各种体液和神经化学物质需要完美相互作用以实现推进性动力。肠梗阻被定义为无论其病理生理学如何，胃肠内容物均不存在向口的推进性运动。本综述描述了肠梗阻的潜在病因。讨论了可用于临床的促动力药物。选择合适的促动力药物需要了解胃肠动力的复杂性质及其异常情况。
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