Rondina Matthew T, Raphael Kalani, Pendleton Robert, Sande Merle A
Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA.
J Gen Intern Med. 2006 Jul;21(7):C1-3. doi: 10.1111/j.1525-1497.2006.00455.x.
Endovascular infections are 1 cause of fever of unknown origin. We describe a diagnostically challenging case of cryptogenic abdominal aortitis from Streptococcus pneumoniae and Enterobacter aerogenes. A 72-year-old male presented with epigastric pain, fevers, and chills. A computed tomography scan demonstrated enlargement and ulceration of the distal abdominal aorta, prompting urgent vascular surgery. Intraoperative tissue cultures grew S. pneumoniae and E. aerogenes and gatifloxacin was administered for 6 weeks. Spontaneous abdominal aortitis is uncommon and usually due to a single pathogen. This is the second reported case of polymicrobial infectious aortitis and to date, Enterobacter has only been reported in infected aortic grafts. Clinicians should maintain a high index of suspicion for infectious aortitis as the mortality, if only treated medically, approaches 100%.
血管内感染是不明原因发热的原因之一。我们描述了一例由肺炎链球菌和产气肠杆菌引起的隐源性腹主动脉炎,诊断颇具挑战性。一名72岁男性出现上腹部疼痛、发热和寒战。计算机断层扫描显示腹主动脉远端增粗和溃疡,促使进行紧急血管手术。术中组织培养培养出肺炎链球菌和产气肠杆菌,并给予加替沙星治疗6周。自发性腹主动脉炎并不常见,通常由单一病原体引起。这是第二例报告的多微生物感染性主动脉炎病例,迄今为止,产气肠杆菌仅在感染的主动脉移植物中被报道过。临床医生应高度怀疑感染性主动脉炎,因为仅采用药物治疗时死亡率接近100%。