Bhutani Manisha, Pathak Ashutosh Kumar, Sengar Manju, Gupta S Datta, Jain Paresh, Thulkar Sanjay, Kochupillai Vinod
Department of Medical Oncology, Institute Rotary Cancer Hospital, New Delhi, India.
Cancer Invest. 2006 Apr-May;24(3):278-82. doi: 10.1080/07357900600629559.
We report a rare case of multifocal osteosarcoma (MFOS) with involvement of skeleton, lung, bone marrow, and soft tissues, presenting with paraparesis, cranial nerve palsies, subcutaneous nodules, anemia, and thrombocytopenia. MFOS with involvement of unusual sites presents problems in diagnosis and has a poor prognosis. The literature on 11 cases of MFOS with extraosseus, extrapulmonary involvement reported previously has been reviewed.
我们报告了一例罕见的多灶性骨肉瘤（MFOS），其累及骨骼、肺、骨髓和软组织，表现为双下肢轻瘫、颅神经麻痹、皮下结节、贫血和血小板减少。累及不寻常部位的MFOS在诊断上存在问题，且预后较差。我们回顾了先前报道的11例伴有骨外、肺外累及的MFOS病例的文献。
