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准分子激光上皮下角膜磨镶术后的龟分枝杆菌角膜炎

Mycobacterium chelonae keratitis after laser-assisted subepithelial keratectomy.

作者信息

Rodriguez Brandon, Holzinger Karl A, Le Lam H, Winkle R Kevin, Allen Ronald D

机构信息

Tripler Army Medical Center, Department of Ophthalmology, Honolulu, Hawaii 96789, USA.

出版信息

J Cataract Refract Surg. 2006 Jun;32(6):1059-61. doi: 10.1016/j.jcrs.2006.03.011.

DOI:10.1016/j.jcrs.2006.03.011
PMID:16814072
Abstract

A 24-year-old man with myopic astigmatism had uncomplicated laser-assisted subepithelial keratectomy (LASEK) in October 2004. Approximately 4 weeks later, a foreign-body sensation and redness developed in the left eye. A paracentral anterior stromal infiltrate was observed, and Gram stain on the day of presentation showed branching filamentous gram-positive rods. Cultures subsequently grew Mycobacterium chelonae. Topical tobramycin 15 mg/mL, azithromycin 2 mg/mL, amikacin 25 mg/mL, and cefazolin 50 mg/mL were initiated based on Gram stain results. We believe this is the first documented case of M chelonae keratitis after LASEK.

摘要

一名24岁的近视散光男性于2004年10月接受了无并发症的准分子激光上皮瓣下角膜磨镶术(LASEK)。大约4周后,左眼出现异物感和眼红。观察到角膜旁中央前基质浸润,就诊当天革兰氏染色显示为分支丝状革兰氏阳性杆菌。随后培养出龟分枝杆菌。根据革兰氏染色结果,开始局部使用15mg/mL的妥布霉素、2mg/mL的阿奇霉素、25mg/mL的阿米卡星和50mg/mL的头孢唑林。我们认为这是LASEK术后首例有记录的龟分枝杆菌角膜炎病例。

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