细胞迁移过程中黏附、突出和收缩的整合。
Integrating adhesion, protrusion, and contraction during cell migration.
作者信息
Schwartz Martin A, Horwitz Alan Rick
机构信息
Department of Microbiology, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.
出版信息
Cell. 2006 Jun 30;125(7):1223-5. doi: 10.1016/j.cell.2006.06.015.
PMID:16814706
Abstract
Cell migration is fastest when the strength of the adhesion between the cell and the substrate is neither too strong nor too weak. In this issue of Cell, reveal how adhesion and cytoskeletal dynamics are integrated to optimize migration speed.
摘要
当细胞与底物之间的黏附强度既不太强也不太弱时，细胞迁移速度最快。在本期《细胞》杂志中，揭示了黏附与细胞骨架动力学是如何整合以优化迁移速度的。
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