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澳大利亚注射吸毒者中的 HIV 流行率:方法学综述。

HIV prevalence among IDUs in Australia: a methodological review.

机构信息

Epidemiology Unit, National Centre in HIV Epidemiology & Clinical Research, 376 Victoria Street, Sydney, NSW, 2010.

出版信息

Drug Alcohol Rev. 1993;12(2):175-84. doi: 10.1080/09595239300185611.

Abstract

A review was carried out of Australian studies which have measured the prevalence of HIV infection among injecting drug users (IDUs). The review considered published studies which had reported on serologically-determined HIV prevalence. There were five studies reported from specialized sexually-transmissible disease of HIV clinics, five studies reported from health services aimed at IDUs, three studies reported from other health services and one multi-centre behavioural study. The main findings from the studies were that HIV prevalence in IDUs has been low in Australia, apart from in male IDUs who also had homosexual contact. HIV prevalence ranged from 20 to 24% in male IDUs reporting homosexual contact and from 0 to 5% in other IDUs.The studies, while reflecting a range of research methodologies, are subject to a number of limitations. Most of the studies did not provide detailed analyses of HIV prevalence by age and sex or behavioural factors, and several studies used sampling frames which were not clearly defined. There is little available information on temporal trends in seroprevalence and geographical comparisons are rendered difficult by differences in the study methodology. Adoption of standardized, continuing seroprevalence surveys on IDUs would provide a better means of monitoring the occurrence of HIV infection in this group, which has been a key determinant of the course of the HIV epidemic in a number of Western countries.

摘要

对澳大利亚已发表的研究进行了综述,这些研究旨在测量注射吸毒者(IDU)中 HIV 感染的流行率。综述考虑了已报告血清学 HIV 流行率的研究。有五项研究来自专门针对 HIV 性传播疾病的诊所,五项研究来自针对 IDU 的卫生服务机构,三项研究来自其他卫生服务机构,一项多中心行为研究。研究的主要发现是,除了同时有同性恋接触的男性 IDU 外,澳大利亚 IDU 中的 HIV 流行率较低。报告同性恋接触的男性 IDU 的 HIV 流行率范围为 20%至 24%,而其他 IDU 的流行率为 0%至 5%。这些研究虽然反映了各种研究方法,但存在许多局限性。大多数研究没有按年龄、性别或行为因素详细分析 HIV 流行率,并且有几项研究使用的抽样框架不明确。有关血清阳性率的时间趋势的信息很少,并且由于研究方法的差异,地理比较也很困难。对 IDU 进行标准化、持续的血清阳性率调查将是监测该人群中 HIV 感染发生情况的更好方法,这是许多西方国家 HIV 流行进程的关键决定因素。

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