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再生大鼠肝脏中的复制前酶变化

Prereplicative enzymic changes in regenerating rat liver.

作者信息

Ebina Y, Iwai H, Fukui N, Otsuka H, Miura Y

出版信息

J Biochem. 1975 Mar;77(3):641-5. doi: 10.1093/oxfordjournals.jbchem.a130766.

DOI:10.1093/oxfordjournals.jbchem.a130766
PMID:168185
Abstract

After partial hepatectomy in rats, the following changes in enzymic activities were observed in the remnant liver during the prereplicative period. In the initial period of the prereplicative process, soon after removal of part of the liver, ornithine decarboxylase [EC 4.1.1.17] and IMP dehydrogenase [EC 1.2.1.14] increase. Subsequently, for entry into the S period, thymidine kinase [EC 2.7.1.75] increases simultaneously with increase in the intracellular cyclic AMP level and decrease in its phosphodiesterase [EC 3.1.4.17].

摘要

大鼠部分肝切除术后,在复制前期观察到残余肝脏中酶活性有以下变化。在复制前期过程的初始阶段,即切除部分肝脏后不久,鸟氨酸脱羧酶[EC 4.1.1.17]和肌苷酸脱氢酶[EC 1.2.1.14]活性增加。随后,为进入S期,胸苷激酶[EC 2.7.1.75]活性增加,同时细胞内环磷酸腺苷水平升高,其磷酸二酯酶[EC 3.1.4.17]活性降低。

相似文献

1
Prereplicative enzymic changes in regenerating rat liver.再生大鼠肝脏中的复制前酶变化
J Biochem. 1975 Mar;77(3):641-5. doi: 10.1093/oxfordjournals.jbchem.a130766.
2
Effects of partial and sham hepatectomy on ornithine decarboxylase and thymidine kinase activities and mRNA contents.部分肝切除术和假手术对鸟氨酸脱羧酶及胸苷激酶活性和mRNA含量的影响。
Biochem Int. 1990;20(4):761-5.
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Sequential changes in ornithine decarboxylase thymidine kinase, and other enzyme activities in regenerating liver in rats on controlled feeding schedules.在控制进食时间表的情况下,大鼠再生肝中鸟氨酸脱羧酶、胸苷激酶及其他酶活性的顺序变化。
Life Sci. 1977 May 1;20(9):1509-19. doi: 10.1016/0024-3205(77)90442-8.
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Pleiotypic responses of regenerating liver.
Adv Enzyme Regul. 1976;14:393-405. doi: 10.1016/0065-2571(76)90023-6.
5
Relationship between plasma and hepatic cytosolic levels of ornithine decarboxylase (ODC) and thymidine kinase (TK) in 70% hepatectomized rats.70%肝切除大鼠血浆与肝脏胞质中鸟氨酸脱羧酶(ODC)和胸苷激酶(TK)水平之间的关系。
Dig Dis Sci. 1991 Mar;36(3):289-92. doi: 10.1007/BF01318198.
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Effect of 3,5,3'-L-triiodothyronine on hepatic ornithine decarboxylase and thymidine kinase activity in rat after partial hepatectomy.3,5,3'-L-三碘甲状腺原氨酸对大鼠部分肝切除术后肝脏鸟氨酸脱羧酶和胸苷激酶活性的影响。
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The possible cyclic AMP-dependence of an early prereplicative event that determines mitosis in regenerating rat liver.
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Lack of effect of portacaval shunt on ornithine decarboxylase activity in regenerating rat liver.门腔静脉分流术对大鼠再生肝中鸟氨酸脱羧酶活性无影响。
Proc Soc Exp Biol Med. 1975 Nov;150(2):380-4. doi: 10.3181/00379727-150-39040.
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Cyclic adenosine 3',5'-monophosphate phosphodiesterase activity in normal, differentiating, regenerating, and neoplastic liver.正常、分化、再生及肿瘤性肝脏中3',5'-环磷酸腺苷磷酸二酯酶活性
Cancer Res. 1973 Feb;33(2):356-61.

引用本文的文献

1
Different calcium requirements for proliferation of conditionally and unconditionally tumorigenic mouse cells.条件性和无条件致瘤性小鼠细胞增殖所需的不同钙含量
Proc Natl Acad Sci U S A. 1976 May;73(5):1651-4. doi: 10.1073/pnas.73.5.1651.
2
The different actions of normal and supranormal calcium concentrations on the proliferation of BALB/c 3T3 mouse cells.正常钙浓度和超正常钙浓度对BALB/c 3T3小鼠细胞增殖的不同作用。
In Vitro. 1976 Jul;12(7):479-84. doi: 10.1007/BF02796490.
3
The regulation of cell proliferation by calcium and cyclic AMP.
钙和环磷酸腺苷对细胞增殖的调节
Mol Cell Biochem. 1979 Nov 1;27(3):155-79. doi: 10.1007/BF00215364.