Ebina Y, Iwai H, Fukui N, Otsuka H, Miura Y
J Biochem. 1975 Mar;77(3):641-5. doi: 10.1093/oxfordjournals.jbchem.a130766.
After partial hepatectomy in rats, the following changes in enzymic activities were observed in the remnant liver during the prereplicative period. In the initial period of the prereplicative process, soon after removal of part of the liver, ornithine decarboxylase [EC 4.1.1.17] and IMP dehydrogenase [EC 1.2.1.14] increase. Subsequently, for entry into the S period, thymidine kinase [EC 2.7.1.75] increases simultaneously with increase in the intracellular cyclic AMP level and decrease in its phosphodiesterase [EC 3.1.4.17].
大鼠部分肝切除术后,在复制前期观察到残余肝脏中酶活性有以下变化。在复制前期过程的初始阶段,即切除部分肝脏后不久,鸟氨酸脱羧酶[EC 4.1.1.17]和肌苷酸脱氢酶[EC 1.2.1.14]活性增加。随后,为进入S期,胸苷激酶[EC 2.7.1.75]活性增加,同时细胞内环磷酸腺苷水平升高,其磷酸二酯酶[EC 3.1.4.17]活性降低。