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初次关节成形术优于移位型股骨颈骨折的内固定术:一项对14项随机研究、2289例患者的荟萃分析。

Primary arthroplasty is better than internal fixation of displaced femoral neck fractures: a meta-analysis of 14 randomized studies with 2,289 patients.

作者信息

Rogmark Cecilia, Johnell Olof

机构信息

Lund University, Department of Orthopaedics, Malmö University Hospital. Malmö, Sweden.

出版信息

Acta Orthop. 2006 Jun;77(3):359-67. doi: 10.1080/17453670610046262.

Abstract

BACKGROUND

The treatment of displaced femoral neck fractures has long been debated. 14 randomized controlled studies (RCTs) comparing internal fixation with primary arthroplasty may give material for evidence-based decision making.

METHODS

Computerized databases were searched for RCTs published between 1966 and 2004. 14 RCTs containing 2,289 patients were included in a metaanalysis regarding complications, reoperations and mortality. The analysis was performed with software from the Cochrane collaboration.

RESULTS

Primary arthroplasty leads to significantly fewer major method-related hip complications and reoperations, compared to internal fixation. There was no significant difference in mortality between the two groups at 30 days and 1 year. Most of the studies found better function and less pain after primary arthroplasty.

INTERPRETATION

Primary arthroplasty should be used in most patients with displaced femoral neck fracture. The healthy, lucid individual, 70-80 years old, should be given a total hip arthroplasty. The older, impaired or institutionalized patient would benefit from a hemiarthroplasty.

摘要

背景

移位型股骨颈骨折的治疗长期以来一直存在争议。14项比较内固定与初次关节置换术的随机对照研究(RCT)可为循证决策提供素材。

方法

检索计算机化数据库,查找1966年至2004年间发表的RCT。14项包含2289例患者的RCT纳入了一项关于并发症、再次手术和死亡率的荟萃分析。分析使用Cochrane协作网的软件进行。

结果

与内固定相比,初次关节置换术导致的主要与手术方法相关的髋部并发症和再次手术明显更少。两组在30天和1年时的死亡率无显著差异。大多数研究发现初次关节置换术后功能更好且疼痛更少。

解读

大多数移位型股骨颈骨折患者应采用初次关节置换术。70至80岁健康、神志清醒的个体应行全髋关节置换术。年龄较大、有功能障碍或住院的患者行半髋关节置换术会受益。

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