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直接前路与后外侧入路治疗股骨颈骨折合并肌少症的手术疗效比较

Comparison of surgical efficacy between direct anterior approach and posterolateral approach in the treatment of sarcopenia with femoral neck fractures.

作者信息

Yin Zhaoyang, Hu Qin, Zhang Bin, Yi Jin, Zhang Hailong, Yin Jian

机构信息

Department of Orthopedics, the Affiliated Lianyungang Hospital of Xuzhou Medical University (The First People's Hospital of Lianyungang), Lianyungang, 222000, China.

Department of Orthopedics, the Affiliated Jiangning Hospital with Nanjing Medical University, Nanjing, 211100, China.

出版信息

BMC Geriatr. 2024 Dec 19;24(1):1021. doi: 10.1186/s12877-024-05621-x.

Abstract

BACKGROUND

Femoral neck fracture (FNF) is a prevalent injury among the elderly, associated with significant morbidity and mortality. Total joint arthroplasty (TJA) has markedly enhanced the quality of life for many patients; however, the benefits of the direct anterior approach (DAA), which has gained popularity in recent years, remain a subject of debate. Sarcopenia frequently occurs in patients with FNF and is linked to adverse surgical outcomes. This study aims to compare the effects of the DAA and the posterolateral approach (PLA) on the efficacy of TJA surgery in patients with FNF who also present with sarcopenia.

METHODS

This study retrospectively analyzed the clinical data of patients with FNF who underwent total hip arthroplasty (THA) using either DAA or PLA from December 2019 to December 2022. A total of 141 individuals were included, comprising 52 in the DAA group and 89 in the PLA group. The cross-sectional area (cm²) of the musculature at the pedicle level of the 12th thoracic vertebra (T12) was measured using chest computed tomography (CT). The skeletal muscle index (SMI) was calculated by dividing the cross-sectional area of the muscle at the T12 pedicle level by the square of the individual's height. Sarcopenia was diagnosed when both grip strength and SMI values fell below the diagnostic cutoff. The study compared various factors, including age, gender, SMI, body mass index (BMI), American Society of Anesthesiologists (ASA) classification, operation time, incision length, blood loss, blood transfusion, hemoglobin drop, albumin drop, postoperative time to ambulation, length of hospitalization, visual analogue scale (VAS) score, Harris score at one and six months post-surgery, complications, revision rate, one-year survival rate following surgery, and patient satisfaction.

RESULTS

There were no statistically significant differences between the two groups regarding gender, age, SMI, BMI, ASA, operation time, blood transfusion, VAS score six months post-surgery, revision rate, satisfaction, and survival rate (P > 0.05). The incision length, blood loss, hemoglobin drop, albumin drop, hospitalization duration, VAS score, and complication rate one month after the operation in the DAA group were all significantly lower than those in the PLA group (P < 0.001). Additionally, the Harris scores at one month and six days post-operation were superior in the DAA group compared to the PLA group (P < 0.001). Furthermore, the incidence of complications in the DAA group was lower than that in the PLA group (P = 0.041). Univariate and multivariate Cox regression analyses indicated that age was an independent risk factor for patients' mortality risk (95% CI: 1.064-1.479, P = 0.007).

CONCLUSION

DAA results in reduced surgical trauma, alleviates postoperative pain, decreases the incidence of complications, enhances the recovery of patients' mobility functions, shortens hospital stays, and is particularly suitable for FNF patients with sarcopenia.

摘要

背景

股骨颈骨折(FNF)在老年人中是一种常见损伤,与显著的发病率和死亡率相关。全关节置换术(TJA)显著提高了许多患者的生活质量;然而,近年来颇受青睐的直接前路入路(DAA)的益处仍存在争议。肌肉减少症在FNF患者中经常发生,并与不良手术结局相关。本研究旨在比较DAA和后外侧入路(PLA)对合并肌肉减少症的FNF患者TJA手术疗效的影响。

方法

本研究回顾性分析了2019年12月至2022年12月期间采用DAA或PLA行全髋关节置换术(THA)的FNF患者的临床资料。共纳入141例患者,其中DAA组52例,PLA组89例。使用胸部计算机断层扫描(CT)测量第12胸椎(T12)椎弓根水平肌肉组织的横截面积(cm²)。骨骼肌指数(SMI)通过将T12椎弓根水平肌肉的横截面积除以个体身高的平方来计算。当握力和SMI值均低于诊断阈值时诊断为肌肉减少症。本研究比较了各种因素,包括年龄、性别、SMI、体重指数(BMI)、美国麻醉医师协会(ASA)分级、手术时间。切口长度、失血量、输血情况、血红蛋白下降、白蛋白下降、术后下地行走时间、住院时间、视觉模拟评分(VAS)、术后1个月和6个月的Harris评分、并发症、翻修率、术后1年生存率以及患者满意度。

结果

两组在性别、年龄、SMI、BMI、ASA、手术时间、输血、术后6个月VAS评分、翻修率、满意度和生存率方面无统计学显著差异(P>0.05)。DAA组术后1个月的切口长度、失血量、血红蛋白下降、白蛋白下降、住院时间、VAS评分和并发症发生率均显著低于PLA组(P<0.001)。此外,DAA组术后1个月和6个月的Harris评分优于PLA组(P<0.001)。此外,DAA组的并发症发生率低于PLA组(P = 0.041)。单因素和多因素Cox回归分析表明,年龄是患者死亡风险的独立危险因素(95%CI:1.064 - 1.479,P = 0.007)。

结论

DAA可减少手术创伤,减轻术后疼痛,降低并发症发生率,促进患者活动功能恢复,缩短住院时间,特别适用于合并肌肉减少症的FNF患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/469d/11660708/99a54747f397/12877_2024_5621_Fig1_HTML.jpg

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