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青少年发作性与持续性抑郁症在成年早期的转归。

The outcome of episodic versus persistent adolescent depression in young adulthood.

作者信息

Steinhausen Hans-Christoph, Haslimeier Claudia, Winkler Metzke Christa

机构信息

Department of Child and Adolescent Psychiatry, University of Zurich, Neumuensterallee 9, CH-8032 Zurich, Switzerland.

出版信息

J Affect Disord. 2006 Nov;96(1-2):49-57. doi: 10.1016/j.jad.2006.05.019. Epub 2006 Jul 3.

Abstract

OBJECTIVE

Study of the impact of episodic and persistent depression on psychosocial and mental functioning of young adults.

METHODS

In a longitudinal representative community sample, four groups of subjects were identified who were depressed either in pre-adolescence, late adolescence or young adulthood or persistently depressed across time, and compared among each other and with a young adult control group. The 90th percentile on one or two self-reported symptom scales (i.e., the Center for Epidemiological Depression Scale (CES-D) or the Anxious/Depressed subscale of either the Youth Self-Report (YSR) or the Young Adult Self-Report (YASR)) served as the cut-off for the depression groups. Outcome was studied with regard to various psychosocial variables including life events, coping, self-related cognitions, size and efficiency of the social network, perceived parental behaviour, family relations and mental functioning.

RESULTS

For the large majority of psychosocial variables, the persistent depression group showed the most abnormal scores. The YASR profile of mental functioning at outcome of the persistent depression group was also clearly distinguishable by higher scores from all other groups on the majority of scales. On a few scales, the young adult episodic group was not significantly different from the persistent depression group.

CONCLUSION

This study shows that persistent rather than episodic adolescent depression carries a risk for abnormal psychosocial and mental functioning in young adulthood. The study also reflects the burden of young adult depression.

摘要

目的

研究发作性和持续性抑郁症对青年心理社会及精神功能的影响。

方法

在一个具有纵向代表性的社区样本中,确定了四组受试者,他们分别在青春期前、青春期后期或青年期患有抑郁症,或长期持续抑郁,并将他们相互比较,同时与一个青年对照组进行比较。在一个或两个自我报告症状量表(即流行病学抑郁量表(CES-D)或青少年自我报告(YSR)或青年自我报告(YASR)的焦虑/抑郁子量表)上的第90百分位数作为抑郁症组的临界值。研究了包括生活事件、应对方式、自我相关认知、社交网络的规模和效率、感知到的父母行为、家庭关系和精神功能等各种心理社会变量的结果。

结果

对于绝大多数心理社会变量,持续性抑郁症组的得分最为异常。持续性抑郁症组在结局时的YASR精神功能概况在大多数量表上也明显高于所有其他组,得分明显不同。在一些量表上,青年发作性抑郁症组与持续性抑郁症组没有显著差异。

结论

这项研究表明,青少年持续性而非发作性抑郁症会在青年期带来心理社会和精神功能异常的风险。该研究还反映了青年抑郁症的负担。

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