Orsmond Gael I, Seltzer Marsha Mailick
Department of Occupational Therapy, Boston University, 635 Commonwealth Ave., Boston, MA 02215, USA.
J Autism Dev Disord. 2009 Jul;39(7):1053-65. doi: 10.1007/s10803-009-0722-7. Epub 2009 Mar 17.
The purpose of this study was to test a diathesis-stress model of well-being for siblings who have a brother or sister with an autism spectrum disorder (ASD). Data were collected from 57 adolescents and their mothers. Sisters reported higher levels of depressive and anxiety symptoms than brothers. Having a family history of ASDs was associated with depressive, but not anxiety, symptoms. A high level of maternal depression was also associated with more depressive and anxiety symptoms. A diathesis-stress model was partially supported, primarily through the findings that sibling sub-threshold autism characteristics were associated with depressive and anxiety symptoms in siblings, but only in the presence of a high number of stressful life events.
本研究的目的是检验针对有患自闭症谱系障碍（ASD）的兄弟姐妹的幸福感素质-应激模型。研究收集了57名青少年及其母亲的数据。姐妹报告的抑郁和焦虑症状水平高于兄弟。有自闭症谱系障碍的家族史与抑郁症状相关，但与焦虑症状无关。母亲的高度抑郁也与更多的抑郁和焦虑症状相关。素质-应激模型得到了部分支持，主要是通过以下研究结果：兄弟姐妹的亚阈值自闭症特征与兄弟姐妹的抑郁和焦虑症状相关，但仅在存在大量应激性生活事件的情况下。
