Corcoran B M, Ross R P, Fitzgerald G F, Dockery P, Stanton C
Teagasc, Moorepark Food Research Centre, Fermoy, Co. Cork, Ireland.
Appl Environ Microbiol. 2006 Jul;72(7):5104-7. doi: 10.1128/AEM.02626-05.
GroESL-overproducing Lactobacillus paracasei NFBC 338 was dried, and its viability was compared with that of controls. Spray- and freeze-dried cultures overproducing GroESL exhibited approximately 10-fold and 2-fold better survival, respectively, demonstrating the importance of GroESL in stress tolerance, which can be exploited to enhance the technological performance of sensitive probiotic cultures.
过量表达GroESL的副干酪乳杆菌NFBC 338被干燥,并将其活力与对照进行比较。过量表达GroESL的喷雾干燥和冷冻干燥培养物的存活率分别提高了约10倍和2倍,这表明GroESL在应激耐受性方面的重要性,可利用这一点来提高敏感益生菌培养物的技术性能。