Spengos K, Grips E, Karachalios G, Tsivgoulis G, Papadimitriou G
Neurologische Klinik der Universität Athen, Eginition Krankenhaus, Athen, Greece.
Nervenarzt. 2006 Aug;77(8):958-60. doi: 10.1007/s00115-006-2128-5.
In the recent past, pathological gambling has been increasingly reported to be related with dopamine agonist application in patients with Parkinson's disease. We present the case of a female patient whose gambling behavior occurred shortly after reaching the final dose of a combined levodopa and pramipexole therapy and resolved completely after stopping pramipexole. Pathological gambling seems to be a rare and serious but reversible adverse reaction to treatment with dopamine agonists of which clinicians should be aware in patients with Parkinson's disease.