Józefowicz-Korczyńska Magdalena, Lukomski Marek
Katedra Otolaryngologii UM w Lodzi, Uniwersytecki Szpital Kliniczny nr 1 im N Barlickiego w Lodzi.
Otolaryngol Pol. 2006;60(1):45-50.
Elektronystagmographic outcome of visual ocular-motor tests (smooth pursuit, optokinetic, saccadic) in 67 healthy subjects in different age were used for quantitative analysis. Three groups were studied: 16 young (29.8 +/- 5.1 year), 38 middle-aged (53.2 +/- 7.6 year) and 13 elderly (73.6 +/- 4.1 year). A four-channel ENG system (version 2,4 Toennies Nystagliner, Germany), with DC-coupled amplifiers, separately for each eye was used. The pursuit target was driven by predictable sinusoidal target with velocity 29 degrees/s, 38 degrees/s, 49 degrees/s and amplitudes of 15 degrees right and left. Optokinetic nystagmus (OKN) was performed using both clockwise and counterclockwise stimuli with velocity 28 degrees/s and 37 degrees/s. In saccades test targets moved abruptly 15 degrees left and right of the centre. In all tests several parameters were calculated like: morphology, gain, phase, maximum velocity and preponderance, and in saccadic test, saccade latency, duration and accuracy as well. In smooth pursuit test gain decreased with ageing. The differences between ages group (younger-middle-age and younger-elderly) for each target velocity were statistically significant. In this study with our paradigm task there was not significant evidence that age impacts parameters of optokinetic and saccadic tests. The 95% prediction interval (95 PI) was calculated for all tests parameters. These findings suggest that evaluation of electronystagmography outcome especially the diagnosis of smooth pursuit dysfunction should be quantified by the age of the patient and by the target task.
对67名不同年龄段的健康受试者进行视觉眼动测试(平稳跟踪、视动性眼震、扫视)的眼震电图结果进行定量分析。研究了三组:16名年轻人(29.8±5.1岁)、38名中年人(53.2±7.6岁)和13名老年人(73.6±4.1岁)。使用四通道ENG系统(2.4版本,德国托尼斯眼震记录仪),配备直流耦合放大器,每只眼睛单独使用。平稳跟踪目标由可预测的正弦目标驱动,速度为29度/秒、38度/秒、49度/秒,左右振幅为15度。使用顺时针和逆时针刺激,速度分别为28度/秒和37度/秒,进行视动性眼震(OKN)测试。在扫视测试中,目标从中心突然向左和向右移动15度。在所有测试中,计算了几个参数,如:形态、增益、相位、最大速度和优势度,在扫视测试中,还计算了扫视潜伏期、持续时间和准确性。在平稳跟踪测试中,增益随年龄增长而降低。每个目标速度下年龄组(年轻人-中年人、年轻人-老年人)之间的差异具有统计学意义。在本研究的范式任务中,没有显著证据表明年龄会影响视动性和扫视测试的参数。计算了所有测试参数的95%预测区间(95 PI)。这些发现表明,眼震电图结果的评估,尤其是平稳跟踪功能障碍的诊断,应根据患者年龄和目标任务进行量化。