Nicholls M G, Espiner E A, Donald R A
J Clin Endocrinol Metab. 1975 Jul;41(1):186-8. doi: 10.1210/jcem-41-1-186.
The brief (60-min) infusion of a small amount (1.25 mug) of ACTH into 7 normal subjects on an unrestricted sodium intake resulted in a vigorous plasma aldosterone response in each case. This finding suggests that physiologic fluctuations in ACTH may significantly alter aldosterone secretion in normal man.
对7名钠摄入不受限制的正常受试者静脉快速注射少量(1.25微克)促肾上腺皮质激素(ACTH),注射时间为60分钟,结果发现,每位受试者的血浆醛固酮水平均出现显著升高。这一结果表明,促肾上腺皮质激素的生理波动可能会显著改变正常人体内醛固酮的分泌。