Bent John
Department of Otolaryngology, Albert Einstein School of Medicine, New York, NY, USA.
Laryngoscope. 2006 Jul;116(7):1059-70. doi: 10.1097/01.mlg.0000222204.88653.c6.
OBJECTIVES/HYPOTHESIS: To assess how medical advances have impacted the diagnosis, management, and outcomes of pediatric laryngotracheal obstruction, and to describe the advantages of audio-video documentation of stridorous children.
Retrospective.
268 patients were referred for suspected laryngotracheal obstruction during the 30 months between September 1, 1995 and March 1, 1998: 173 had 206 flexible fiberoptic laryngoscopies, and 160 had 273 direct laryngoscopies. One hundred and forty-one children were identified with laryngotracheal obstruction, yielding 40 different diagnoses that could be classified into 9 major categories. Thirty-six children (25.5%) had multiple sites of upper airway obstruction.
138 children had follow-up >1 month. Twelve children died (8.7%), leaving 126 survivors (mean follow-up=21.1 months). Outcomes were classified as resolved (44.2%), improved (37.0%), stable (9.4%), failed (0.7%), or death (8.7%). Better outcomes were seen in more readily treated diagnostic categories, such as tracheobronchial foreign body, chronic laryngitis, and suprastomal granulation tissue; laryngeal stenosis, tracheomalacia, and recurrent respiratory papillomatosis, had less favorable outcomes (P<.001). The former group also showed superior outcome compared to laryngomalacia (P<.001) and vocal cord mobility disorders (P=.004). Ninety-four patients (68.1%) had comorbidities complicating their management. Comorbid conditions were universal among deceased patients and least common in the resolved outcomes category (56.7%), supporting the premise that patients with poor outcomes are more likely to have comorbidities than patients with resolution of laryngotracheal symptoms (P=.034).
Audio-video recording of pediatric laryngotracheal obstruction offers numerous advantages. Children classified into an array of diagnostic categories usually have favorable outcomes, but opportunities for continued advances exist, particularly regarding management of comorbidity and chronic obstruction.
目的/假设:评估医学进展如何影响小儿喉气管阻塞的诊断、管理及治疗结果,并描述对喘鸣儿童进行视听记录的优势。
回顾性研究。
在1995年9月1日至1998年3月1日的30个月期间,268例疑似喉气管阻塞患者被转诊:173例接受了206次可弯曲纤维喉镜检查,160例接受了273次直接喉镜检查。141名儿童被确诊为喉气管阻塞,得出40种不同诊断,可分为9大类。36名儿童(25.5%)存在上气道多部位阻塞。
138名儿童随访时间超过1个月。12名儿童死亡(8.7%),126名存活(平均随访时间=21.1个月)。治疗结果分为治愈(44.2%)、改善(37.0%)、稳定(9.4%)、失败(0.7%)或死亡(8.7%)。在更容易治疗的诊断类别中,如气管支气管异物、慢性喉炎和造口上肉芽组织,治疗结果更好;喉狭窄、气管软化和复发性呼吸道乳头状瘤病的治疗结果较差(P<0.001)。与喉软化症(P<0.001)和声带活动障碍(P=0.004)相比,前一组的治疗结果也更优。94例患者(68.1%)存在使治疗复杂化的合并症。合并症在死亡患者中普遍存在,在治愈结果类别中最不常见(56.7%),这支持了与喉气管症状缓解的患者相比,治疗结果不佳的患者更可能有合并症这一前提(P=0.034)。
小儿喉气管阻塞的视听记录具有诸多优势。分类为一系列诊断类别的儿童通常有良好的治疗结果,但仍有持续进步的空间,尤其是在合并症和慢性阻塞的管理方面。