O'Hanlan Katherine A, Dibble Suzanne L, Fisher Deidre T
Gynecologic Oncology Associates, 4370 Alpine Rd. Suite 104, Portola Valley, CA 94028, USA.
Gynecol Oncol. 2006 Dec;103(3):938-41. doi: 10.1016/j.ygyno.2006.05.036. Epub 2006 Jul 10.
We sought to analyze surgical results of women with uterine cancers having TLH+/-staging, stratifying data by body mass index (BMI).
This is a retrospective analysis of data from 9 years, using Pearson and Spearman correlations, ANOVA and Fisher's Exact Test with significance at P<0.05, stratifying by BMI (kg/m2): underweight (<18.5 kg/m2), ideal (18.5-24.9 kg/m2), overweight (25 to 29.9 kg/m2), obese (30 to 39.9 kg/m2) and morbidly obese (40 kg/m2 or more).
Of 702 patients having TLH over 9 years, 90 patients had uterine pathology. Two (2%) procedures were converted to laparotomy due to unsuspected widespread metastasis and excluded from analysis. BMI ranged from 18 to 60 kg/m2, with 31 patients having ideal, 19 having overweight and 38 having obese BMI. Of these, 19 patients had hyperplasia, while 63 had endometrial carcinoma, 1 had both ovarian and endometrial carcinoma and 5 had sarcoma. Of these 88 patients, 61 had TLH while 27 patients had indicated pelvic and aortic node dissection. The mean age was 60 years, and mean parity was 1.5 for all BMI groups. There were no significant differences in mean duration of surgery (150 min), blood loss (129 cm3) and days in hospital (1.7 days) for all BMI groups. There was no significant difference in uterine weight (140 gm) or number of nodes dissected (21 nodes). Complications occurred in 4 patients (4.5%): 1 diverticulitis, 1 ureteral injury, 1 laparotomy for bleeding and 1 incisional hernia.
Total laparoscopic hysterectomy is feasible and safe for women with uterine neoplasia for every BMI category and extends the benefits of minimally invasive hysterectomy to more women, regardless of BMI.
我们试图分析接受全腹腔镜子宫切除术(TLH)±分期的子宫癌女性患者的手术结果,并按体重指数(BMI)对数据进行分层。
这是一项对9年数据的回顾性分析,使用Pearson和Spearman相关性分析、方差分析以及Fisher精确检验,显著性水平为P<0.05,按BMI(kg/m²)分层:体重过轻(<18.5 kg/m²)、理想体重(18.5 - 24.9 kg/m²)、超重(25至29.9 kg/m²)、肥胖(30至39.9 kg/m²)和病态肥胖(40 kg/m²及以上)。
在9年期间接受TLH的702例患者中,90例有子宫病变。2例(2%)手术因意外发现广泛转移而转为剖腹手术,被排除在分析之外。BMI范围为18至60 kg/m²,其中31例患者BMI为理想体重,19例超重,38例肥胖。其中,19例有增生,63例有子宫内膜癌,1例同时患有卵巢癌和子宫内膜癌,5例有肉瘤。在这88例患者中,61例行TLH,27例进行了盆腔和主动脉淋巴结清扫。所有BMI组的平均年龄为60岁,平均产次为1.5。所有BMI组的平均手术时间(150分钟)、失血量(129 cm³)和住院天数(1.7天)均无显著差异。子宫重量(140克)或清扫淋巴结数量(21个)也无显著差异。4例患者(4.5%)出现并发症:1例憩室炎、1例输尿管损伤、1例因出血行剖腹手术和1例切口疝。
对于每一个BMI类别的子宫肿瘤女性患者,全腹腔镜子宫切除术都是可行且安全的,并且将微创子宫切除术的益处扩展到了更多女性,无论其BMI如何。