Fayyad Luma M, Al-Jader Khalaf M, Al-Hawwari Belal A
Department of Histopathology and Cytology, King Hussein Medical Center, Amman 11831, Jordan.
Saudi Med J. 2006 Jul;27(7):1060-2.
Histologic variants of prostatic carcinoma are readily recognized. In this report, we describe a rare variant, adenoid cystic carcinoma, in a 75-year-old man previously diagnosed to have transitional cell carcinoma of the urinary bladder. The diagnosis of adenoid cystic carcinoma was made by the characteristic microscopic features of the tumor morphologically and immunohistochemically. Two months later he was found to have metastatic disease. The patient's treatment consisted of chemotherapy in combination with prednisone and hormonal therapy. Five and a half months after diagnosis, he died with metastatic disease. Making this case unique is the asynchronous occurrence of this variant with transitional cell carcinoma of the urinary bladder, which has never been reported in the literature. We discussed the histopathologic and immunohistochemical features of adenoid cystic carcinoma of the prostate with review of literature.
前列腺癌的组织学变异型很容易识别。在本报告中，我们描述了一名75岁男性患者，其患有罕见的腺样囊性癌变异型，该患者此前被诊断患有膀胱移行细胞癌。腺样囊性癌的诊断是通过肿瘤形态学和免疫组织化学的特征性微观表现做出的。两个月后，他被发现出现了转移性疾病。患者的治疗包括化疗联合泼尼松和激素治疗。诊断五个半月后，他因转移性疾病死亡。该病例的独特之处在于这种变异型与膀胱移行细胞癌的异步发生，这在文献中从未有过报道。我们结合文献讨论了前列腺腺样囊性癌的组织病理学和免疫组织化学特征。
