He Lin, Metter Christopher, Margulis Vitaly, Kapur Payal
Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Case Rep Pathol. 2021 May 4;2021:5520581. doi: 10.1155/2021/5520581. eCollection 2021.
Basal cell carcinoma (BCC) is a rare nonacinar variant of prostatic carcinoma. In spite of prostatic acinar adenocarcinoma being one of the most common carcinomas in prostate, <100 prostatic BCC cases have been reported to date. Adenoid cystic/cribriform histology has been described in varying proportions to occur in prostatic BCC and is reported to be associated with aggressive behavior and high risk of metastasis. Herein, we present a case of prostatic BCC with adenoid cystic morphology, comprehensively describe its immunohistochemical and gene rearrangement findings, discuss its differential diagnosis, and review the literature of this rare entity.
基底细胞癌（BCC）是前列腺癌一种罕见的非腺泡型变体。尽管前列腺腺泡腺癌是前列腺最常见的癌之一，但迄今为止报道的前列腺基底细胞癌病例不足100例。腺样囊性/筛状组织学在前列腺基底细胞癌中以不同比例出现，据报道与侵袭性行为和高转移风险相关。在此，我们报告一例具有腺样囊性形态的前列腺基底细胞癌病例，全面描述其免疫组化和基因重排结果，讨论其鉴别诊断，并复习有关这一罕见实体的文献。
