King W W, Cave D R
Department of Medicine, University Hospital, Boston University Medical Center, Massachusetts.
Am J Med. 1991 Oct;91(4):425-8. doi: 10.1016/0002-9343(91)90162-q.
Tetanus is often accompained by autonomic instability, rendering hemodynamic management difficult. Death is frequently secondary to an inability to control this instability. A variety of modalities have been used to stabilize the cardiovascular system, but all are not ideal. Esmolol offers theoretical advantages over other modalities. We report a case of severe tetanus in which a continuous infusion of esmolol was effective in controlling the autonomic instability.
破伤风常伴有自主神经功能不稳定，导致血流动力学管理困难。死亡往往是由于无法控制这种不稳定所致。已采用多种方法来稳定心血管系统，但都不尽理想。艾司洛尔比其他方法具有理论上的优势。我们报告一例严重破伤风病例，持续输注艾司洛尔有效地控制了自主神经功能不稳定。
