Suppr超能文献

钝性头部外伤后重复头颅计算机断层扫描的效用:一项系统评价

Utility of repeat head computed tomography after blunt head trauma: a systematic review.

作者信息

Wang Marjorie C, Linnau Ken F, Tirschwell David L, Hollingworth William

机构信息

Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA.

出版信息

J Trauma. 2006 Jul;61(1):226-33. doi: 10.1097/01.ta.0000197385.18452.89.

Abstract

BACKGROUND

Repeat head computed tomography (CT) is standard practice for head-injured patients at many trauma centers. Utilization of CT has increased over time, yet effects on outcome and associated risks are unknown. We systematically reviewed the literature to determine the incidence of progression of injury on repeat CT and resulting treatment changes.

METHODS

Studies were included from Medline, Embase, and a hand search of citations in reviewed articles. Main outcome measures were progression of injury on repeat CT and resulting intervention. Data were abstracted from 30 eligible studies and discrepancies were settled by consensus.

RESULTS

Progression of injury on repeat CT was evident in 8 to 67% of patients in the included studies. Neurosurgical intervention resulting subsequent to a repeat CT occurred in 0 to 54% of patients. More severe traumatic brain injury, defined by Glasgow Coma Scale, was associated with a higher proportion of patients with progression of injury on CT and subsequent neurosurgical interventions. Risk factors associated with progression of injury on CT or resulting intervention were inconsistently reported, but coagulopathy and injury severity were most commonly reported. Few studies reported changes in nonsurgical management, in-hospital disposition, or adverse events associated with obtaining repeat CTs.

CONCLUSION

Indications for repeat head CT after traumatic brain injury are unclear. The wide range of reported injury progression on CT and resulting surgical and medical treatment changes suggest there may be a subset of patients who benefit from repeat CT. Further research should stratify by severity of traumatic brain injury, clearly define inclusion and exclusion criteria, address selection bias, quantify progression of injury on CT, determine factors predictive of injury progression and intervention, and assess risks associated with repeat CT.

摘要

背景

在许多创伤中心,对头部受伤患者进行重复头颅计算机断层扫描(CT)是标准做法。随着时间的推移,CT的使用有所增加,但对结果的影响和相关风险尚不清楚。我们系统地回顾了文献,以确定重复CT检查时损伤进展的发生率以及由此导致的治疗变化。

方法

纳入来自医学数据库(Medline)、荷兰医学文摘数据库(Embase)的研究以及对综述文章中引用文献的手工检索。主要观察指标为重复CT检查时的损伤进展情况及由此产生的干预措施。从30项符合条件的研究中提取数据,分歧通过协商解决。

结果

在纳入的研究中,8%至67%的患者在重复CT检查时出现损伤进展。重复CT检查后进行神经外科干预的患者比例为0%至54%。根据格拉斯哥昏迷量表定义的更严重的创伤性脑损伤,与CT检查时损伤进展和随后进行神经外科干预的患者比例较高相关。与CT检查时损伤进展或由此产生的干预相关的危险因素报告不一致,但凝血功能障碍和损伤严重程度是最常报告的因素。很少有研究报告非手术治疗、住院处置或与进行重复CT检查相关的不良事件的变化。

结论

创伤性脑损伤后重复头颅CT检查的指征尚不清楚。CT检查中报告的损伤进展范围广泛以及由此导致的手术和药物治疗变化表明,可能有一部分患者从重复CT检查中获益。进一步的研究应根据创伤性脑损伤的严重程度进行分层,明确界定纳入和排除标准,解决选择偏倚问题,量化CT检查时的损伤进展情况,确定预测损伤进展和干预的因素,并评估与重复CT检查相关的风险。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验