Lee W J, Chang K J, Wang S M, Chen K M, How S W
Department of Surgery, College of Medicine, National Taiwan University, Taipei, R.O.C.
J Formos Med Assoc. 1991 Aug;90(8):776-81.
The records of 101 patients with primary small intestinal malignant tumor at NTUH, collected from 1960 to 1989, were reviewed. These patients represented 1.2% of the patients with gastrointestinal cancer at NTUH over the same period. Fourty-two (41.6%) of the cancer patients had lymphomas, 30(29.7%) had adenocarcinomas, 26 (25.7%) had leiomyosarcomas, and 3(3.0%) had carcinoid tumors. The average age at cancer presentation was 47.5 years (range from 3 to 96). The lymphoma patients had an average age of 35.1 years, while adenocarcinoma patients averaged 60.4 years of age. Leiomyosarcoma and carcinoid tumors averaged 51.2 years and 59 years, respectively. There were 65 male patients and 36 female patients, and there was a male predominance in all groups except for the leiomyosarcoma group which had an equal sex ratio. Generally speaking, the incidence rate for the areas involved were similar in the duodenum, jejunum and ileum. However, adenocarcinomas were more common in the duodenum (53%) and 45% of lymphomas were found in the ileum, as were the carcinoid tumors (66%). The most common presenting symptom was abdominal pain (62%), with bleeding second (32%). Obstruction and palpable mass together were present in 29% of the cases. Body weight loss was found in 25% of patients, and 14% of the patients presented with acute abdomen due to intestinal perforation. Laparotomy was the most common diagnostic procedure (60%). Preoperative diagnoses were possible in cases of duodenal and upper intestinal malignancies, but were rarely possible in patients with lower intestinal malignancies. Sixty-eight patients (68%) underwent tumor resection for palliation or cure. The operation mortality was 4%.(ABSTRACT TRUNCATED AT 250 WORDS)
回顾了1960年至1989年在台湾大学医院收集的101例原发性小肠恶性肿瘤患者的记录。这些患者占同期台湾大学医院胃肠道癌患者的1.2%。42例(41.6%)癌症患者患有淋巴瘤,30例(29.7%)患有腺癌,26例(25.7%)患有平滑肌肉瘤,3例(3.0%)患有类癌肿瘤。癌症发病的平均年龄为47.5岁(范围为3至96岁)。淋巴瘤患者的平均年龄为35.1岁,而腺癌患者的平均年龄为60.4岁。平滑肌肉瘤和类癌肿瘤的平均年龄分别为51.2岁和59岁。有65例男性患者和36例女性患者,除平滑肌肉瘤组性别比例相等外,所有组均以男性为主。一般来说,十二指肠、空肠和回肠受累区域的发病率相似。然而,腺癌在十二指肠中更常见(53%),45%的淋巴瘤在回肠中发现,类癌肿瘤也是如此(66%)。最常见的症状是腹痛(62%),其次是出血(32%)。29%的病例同时出现梗阻和可触及肿块。25%的患者体重减轻,14%的患者因肠穿孔出现急腹症。剖腹手术是最常见的诊断方法(60%)。十二指肠和上消化道恶性肿瘤患者术前可以诊断,但下消化道恶性肿瘤患者很少能做到。68例患者(68%)接受了肿瘤切除以缓解症状或治愈。手术死亡率为4%。(摘要截短至250字)