Ciccarelli O, Welch J P, Kent G G
Am J Surg. 1987 Apr;153(4):350-4. doi: 10.1016/0002-9610(87)90575-7.
The medical records of 51 patients with primary small bowel cancer were reviewed. Twenty patients had carcinoid tumors, 17 had adenocarcinomas, 8 had leiomyosarcomas, and 6 had lymphomas. Presenting complaints were protean in nature and only 33 percent of patients had a correct diagnosis at the time of operation. Curative resection was attempted in 55 percent, but most patients presented late in their illness and only 27 percent had localized tumors. Survival has been poor: at most recent follow-up, 59 percent were dead, 14 percent were alive with disease, and 27 percent were alive and well. Earlier diagnosis may improve survival. Patients at risk for these tumors are usually more than 50 years of age with vague complaints such as weight loss, pain, abdominal fullness, and fatigue. They should undergo complete evaluation centered around exhaustive radiographic studies and liberal use of endoscopy.
回顾了51例原发性小肠癌患者的病历。其中20例为类癌肿瘤，17例为腺癌，8例为平滑肌肉瘤，6例为淋巴瘤。临床表现多种多样，只有33%的患者在手术时得到了正确诊断。55%的患者尝试进行了根治性切除，但大多数患者就诊时病情已较晚，只有27%的患者肿瘤局限。生存率一直很低：在最近一次随访时，59%的患者已死亡，14%的患者带瘤存活，27%的患者存活且状况良好。早期诊断可能会提高生存率。这些肿瘤的高危患者通常年龄超过50岁，有体重减轻、疼痛、腹部胀满和疲劳等模糊症状。他们应接受以详尽的影像学检查和广泛使用内镜检查为中心的全面评估。
