Battaglia D, Chieffo D, Lettori D, Perrino F, Di Rocco C, Guzzetta F
Child Neuropsychiatry, Catholic University, Rome, Italy.
Childs Nerv Syst. 2006 Aug;22(8):744-59. doi: 10.1007/s00381-006-0151-2. Epub 2006 Jul 12.
Although the neurocognitive assessment in children as in the adults is an important step before and after surgery, in the literature, the data about pre- and postoperative neurocognitive evaluations in children are very few.
The purpose of this paper is to consider some peculiar aspects of the neurocognitive assessment during development, and report literature data about neuropsychological outcome of epileptic children treated with focal resection and hemispherectomy.
The second section concerns our personal experience about a cohort of 45 children with refractory epilepsy operated on before 7 years. The results suggest that early surgical treatment is generally effective for seizure control and behavior improvement in children with refractory epilepsy. Concerning cognitive outcome, we found that the neurocognitive level was unchanged in the majority of the patients.
We underline the importance of multicentric studies with standardized neuropsychological assessments in large series of young children.
尽管儿童和成人的神经认知评估都是手术前后的重要步骤,但在文献中,关于儿童术前和术后神经认知评估的数据非常少。
本文旨在探讨发育过程中神经认知评估的一些特殊方面,并报告有关接受局灶性切除和大脑半球切除术治疗的癫痫儿童神经心理学结果的文献数据。
第二部分涉及我们对45例7岁前接受手术的难治性癫痫患儿的个人经验。结果表明,早期手术治疗通常对难治性癫痫患儿的癫痫控制和行为改善有效。关于认知结果,我们发现大多数患者的神经认知水平没有变化。
我们强调在大量幼儿中进行标准化神经心理学评估的多中心研究的重要性。