Medical College of Wisconsin, Children's Hospital of Wisconsin, Milwaukee, WI 53226, USA.
Transl Pediatr. 2014 Jul;3(3):208-17. doi: 10.3978/j.issn.2224-4336.2014.04.01.
The term hemispherectomy refers to the complete removal or functional disconnection of a cerebral hemisphere. The technique was initially developed over 85 years ago to treat infiltrating brain tumors but is now used exclusively for medically refractory epilepsy. Hemispherectomy surgery has progressed from an extremely morbid procedure fraught with complications to a fairly routine one performed at most pediatric epilepsy centers with relatively low risk and great efficacy. The author reviews the history and evolution of hemispherectomy surgery, the relevant pathological conditions, as well as outcomes and complications.
半球切除术是指完全切除或功能性切断大脑半球。该技术最初是在 85 年前开发的,用于治疗浸润性脑肿瘤,但现在专门用于治疗药物难治性癫痫。半球切除术已经从一个充满并发症的极其致命的手术发展到一个在大多数儿科癫痫中心都相对常规的手术,风险较低,疗效显著。作者回顾了半球切除术的历史和演变、相关的病理情况以及结果和并发症。